Speaker Profile

Contributions to advancing PM through your leadership in ClinGen, PharmGKB, and CPIC

Ph.D., Professor, Stanford

Dr. Klein is the MPI of the pharmacogenomics knowledgebase (PharmGKB), Clinical Implementation Pharmacogenetics Consortium (CPIC), the Pharmacogenomics Clinical Annotation Tool (PharmCAT) and the Clinical Genomics Resource (ClinGen). She is a Professor in the Departments of Biomedical Data Science and Medicine, and by courtesy, Genetics. Her professional expertise extends over pharmacogenomics, computational biology and bioinformatics. Applications include the development of the PharmGKB, CPIC, PharmCAT, ClinGen and de novo modeling and the structural basis of diseases. Dr. Klein received her from UCSF. She is a fellow in the American Association for the Advancement of Science and American College of Medical Informatics and is actively involved in the Pharmacogenetics Research Network (PGRN), ACMG Secondary Findings Committee and the ISCC PGx Project Group. Dr. Klein is the cofounding and senior chair of the international Pacific Symposium of Biocomputing now in its 29th year and an editor for AI in Precision Oncology.

ClinPGx: A Single Integrated PGx Resource
This talk will discuss the challenge of the separation of pharmacogenomic resources from clinical genomic resources, and present a longterm, conceptual framework for broadly merging and integrating the available PGx resources including PharmGKB, CPIC, PharmCAT and PharmVAR into a single resource, ClinPGx.

 Session Abstract – PMWC 2024 Silicon Valley

Track 1 - January 26 9.00 A.M.-4.30 P.M.

Track Chair:
Kelly E. Caudle, St. Jude

The PMWC 2024 Pharmacogenomics (PGx) Track focuses on advancing standardization in pharmacogenomics to achieve better clinical outcomes. The importance of standardization in PGx cannot be overstated as it can help to improve patient care in several ways. Standardization of clinical laboratory processes can help ensure consistent and accurate test results, which is crucial for making informed clinical decisions. Standardization of reporting can help to ensure that test results are communicated in a clear and understandable manner to clinicians and patients. Standardization of pharmacogenomic test ordering and reimbursement can help to ensure that patients have access to the tests they need, regardless of their location or financial situation. Standardization of PGx education can help to ensure that healthcare professionals have the knowledge and skills they need to use PGx in clinical practice effectively. Finally, clinical pearls and outcome data can help to demonstrate the value of PGx in improving patient outcomes and informing clinical decision-making.

  • PMWC 2024 PGx Award Ceremony:
    Pioneer Honoree: Russ Altman, Stanford
    Pioneer Honoree: Andrea Gaedigk, University of Kansas
    Luminary Honoree: Teri E. Klein, Stanford
  • Standardization: Key to Advancing Precision Medicine
    Opening Talk: Kelly E. Caudle, St. Jude
  • Current and Desired States of Standardization of Clinical Laboratory Processes
    Chair: Andrea Gaedigk, University of Kansas
    - Vicky Pratt, Agena Bioscience
    Chair: Damon Hostin, Illumina
    - Howard McLeod, Utah Tech University
  • Current and Desired States of Standardization of Reporting
    Chair: Chad Bousman, University of Calgary
    - Vicky Pratt, Agena Bioscience
    - Lisa Brown
    - Susanne Haga, Duke
  • Current and Desired States of Standardization of Pharmacogenomic Test Ordering and Reimbursement (PANEL)
    Chair: Sara Rogers, American Society of Pharmacovigilance
    - Jai Patel, Atrium Health
    - Greg Warren, Axene Health Partners
  • Current and Desired State of PGx Education
    Chair: Phil Empey, University of Pittsburgh
    - Teri E. Klein, Stanford
  • Current and Desired State of the Patient Experience in Precision Medicine (PANEL)
    Chair: Avni Santani, LetsGetChecked
    - Kristy Crooks, University of Colorado - Stuart Scott, Stanford
  • Clinical Pearls and Outcome Data: Advancing the Adoption of Pharmacogenomics in Clinical Practice
    Chair: Kelly E. Caudle, St. Jude
    - Larisa H Cavallari, University of Florida
    - Jeff Bishop, University of Minnesota
  • PMWC Showcase
    - Bani Tamraz, UCSF


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