Speaker Profile
M.D., Ph.D., Chief Medical Officer, Guardian Research Network
Biography
As a surgical pathologist and NIHsupported scientist in brain tumor biology, Mark brings a range of experiences as a researcher in biology, clinical development and executive leadership, especially with drugs and biologics requiring biomarkers and companion diagnostics.As a thought leader, Mark has mapped the murine whole genome and positionally cloned the gene that spawned an entire field of immune cell regulation. He also cloned the microorchidia gene, a transgene insertion knockout phenotype that defined a new category of DNA and chromosome maintenance genes.Mark also brings GRN Partners and clients his dynamic experience with EMR and IT systems, including pathology databases, laboratory information systems, clinical trial management systems, imaging systems for radiology and others.
Session Abstract – PMWC 2024 Silicon Valley
Track Chair:
- William Oh, Mount Sinai
Patient-centric data – Real-World Evidence (RWE) and Real-World Data (RWD) - is becoming instrumental in the drug development process and for health care decisions in general. This data is not only informative for the process from discovery to new indications, clinical trial design, and drug development, it also can be of value to monitor post-marketing drug safety and for decision support in clinical practice. As the data becomes a decision driver, science companies and medical organizations are increasingly focused on leveraging RWD and RWE to not only better understand the patient populations using their drugs and the respective outcomes, but also to accelerate clinical decision support. This session will focus on the various aspects of integrating RWE and RWD to support drug development and clinical decision support.
Sessions:
- PMWC 2024 Award Ceremony
Pioneer Honoree: Atul Butte, UCSF
- Fostering Collaboration: Strategies to Enhance Data Sharing in Medical Research (PANEL)
Chair: Craig Eagle, Guardant Health
- Paul Boutros, UCLA
- Atul Butte, UCSF
- George Sledge, Caris Life Sciences
- Erica Galvez, Manifest MedEx - Regulatory Challenges in Collecting and Using Race and Ethnicity Data in Real-World Evidence
Chair: Susan Winkler, Reagan-Udall Center
- Multi-Modal Datasets & RWE/D: Pioneering Tools for Accelerated Biomedical Research
Chair: TBA
- Data Privacy and Security in RWE/D
Chair: Deven McGraw, Invitae
- Christopher Boone, AbbVie
- Susan Stayn, Stanford
- Alexa Berk King, CVS
- Accelerating Drug Development Approvals Using RWE/D (PANEL)
Chair: Maria Karasarides, BMS
- Leo Russo, Pfizer
- Eric Schadt, Ethos AI
- Ashley Brenton, Optum
