Dr. El-Samad’s research group seeks to deliver insights into biological feedback control, unraveling evolutionary successful principles of feedback strategies that are most appropriate for the biological substrate and achieving understanding at the right depth and granularity for forward engineering them with predictable outcomes. A major current focus of her research is to enable measurement of feedback in living cells, synthetic technologies to program cellular function, and theoretical frameworks to quantify biological homeostasis and resilience. Her goal at Altos labs is to rationally reprogram cells to a state of health and resilience.
In this talk, we discuss how cellular therapies can benefit from precise and programmable control. Through this lens, we also discuss how the ambitious future of this field relies on a diverse workforce powering equitable and ethically informed therapeutical advances.
Yael Weiss, Mahzi
Peter Marks, FDA