Gautam is a leader in translational computational biology and a seasoned professional with an impactful 20-year track record in biotech, academia and tech industry. Most recently, Gautam built and headed an inter-disciplinary R&D/Consulting practice of five Ph.D. computational biologists to implement pipelines for analysis of multi-omics datasets including single-cell RNA-seq, CyTOF, proteomics and metabolomics from cross-sectional/longitudinal observation/intervention studies. Gautam advised biotech and pharmaceutical companies on challenges in early-stage target discovery, biomarker analysis and patient stratification for clinical development, and identification of mechanisms of action and resistance to treatments. Prior to that, he spearheaded biomarker research and platform development as Director of Precision Medicine at a biotech to accelerate clinical development of Antigen-specific Immunotherapies. He led the biomarker discovery program in Celiac Disease which resulted in the 1st blood-based diagnostic and an immune response monitoring toolkit to support Phase 2 clinical trials.