Session Abstract – PMWC 2020 Silicon Valley


The PMWC 2020 Wellness & Aging Showcase will provide a 15-minute time slot for selected companies in Wellness and Aging to present their latest technologies to an audience of leading investors, potential clients, and partners. We will hear from selected companies that build innovative solutions and harness the power of digital health, genomics, and data science with the goal to proactively prevent disease, maintain optimal health, and slow down aging.


Confirmed Presenting Companies:

 Session Chair Profile

M.D., Board Member, American Board of Integrative Medicine, Voluntary Assistant Clinical Professor, UCSD Health Sciences

Biography
Marvin Singh is a pioneer in clinical applications of precision health and is one of few physicians in the country who is fellowship trained in Integrative Medicine and Gastroenterology. He has been a faculty member at prestigious universities and enjoys collaborating with scientists and researchers to fine tune his protocols. He is an invited speaker for the American Academy of Anti-Aging Medicine and a contributing faculty to the Andrew Weil Center for Integrative Medicine. He is passionate about educating other physicians regarding how to optimize gut and whole health. As a thought leader in the field, he brings a unique perspective to how medicine will be practiced in the future.


Wellness and Aging Showcase:
UCSD

The primary aim of Precisione Clinic is to help people understand their body, how it works, and what it needs by utilizing cutting edge science, technology, and research to develop highly specific protocols for the purpose of prevention and extending life.

Redefining Precision Healthcare For The Patient
We will outline the key elements of health and chronic illness, while outlining what precision testing can be utilized to help optimize health and prevent disease by providing information that will allow the clinician to create a meaningful clinical protocol.

 Speaker Profile

M.D., COO, BIOAGE

Biography
Eric finds and develops high-impact drug targets and biomarkers via deep molecular phenotyping of human cohort samples and clinically-relevant machine learning and systems biology analytic pipelines. He co-founded BIOAGE to apply these strategies to developing therapies to extend human healthspan and lifespan. Eric was previously an assistant professor at the University of Toronto focusing on biomarker discovery and characterization in high-dimensional datasets from human cohorts. He completed an MD, residency, and research fellowship in computational biology, held a Canada Graduate Scholarship from the CIHR, and was subsequently a CIHR research fellow. Eric is a licentiate of the Medical Council of Canada and a fellow of the Royal College of Physicians and Surgeons of Canada.


Wellness and Aging:
BIOAGE

BIOAGE is a venture-backed company with an innovative computational platform for anti-aging drug discovery and an accomplished, interdisciplinary team from biotech, academia, and pharma that is creating and advancing a broad pipeline of therapeutics.

Chronic Disease Through The Lens Of Aging: Omics Studies Of Healthy Aging Cohorts Reveal New Drug Targets In Multiple Therapeutic Areas
- Aging is the major risk factor for many chronic diseases, yet target discovery efforts do not generally take this into account
- Deep omic phenotyping of prospective healthy human aging cohorts with decades of follow-up reveals key pathways driving aging
- We find that studying aging directly yields novel and promising drug targets in therapeutic areas including neurodegeneration, cardiovascular disease, etc

 Speaker Profile

M.D., Physician/Owner, Personalized Lifestyle Medicine Center by Metagenic

Biography
Joseph Lamb completed his education at the Medical College of Virginia in Richmond, VA and his Internal Medicine residency at Presbyterian University of Pennsylvania Medical Center. Board-certified in Internal Medicine and Holistic Medicine/Integrative Medicine, he is a Founding Diplomate of the American Board of Integrative and Holistic Medicine. In 2013, he achieved certification as an Institute for Functional Medicine Certified Practitioner. Dr. Lamb is the Principal Investigator for LIFE-HOUSE – a Lifestyle Intervention and Functional Evaluation: a Health OUtcomes SurvEy. Past experiences include 17 years of private practice in Alexandria, Virginia and 4 years as Senior Clinician at the Hypertension Institute in Nashville, TN. Dr Lamb has been the Primary Investigator in over 75 clinical studies to date. He has lectured internationally and authored multiple book chapters and academic papers. Recently, he co-authored a text-book, Vascular Biology for the Clinician


Wellness and Aging Showcase:
Personalized Lifestyle Medicine Center by Metagenic

The Personalized Lifestyle Medicine Center is an incubator for the best practices related to function, wellness and the delivery of care. We are engaged in gathering research evidence to prove the value of these advances to the medical community, employers, insurers and public policy makers.

LIFEHOUSE: Personalized Interventions Improving Health Outcomes
LIFEHOUSE (Lifestyle Intervention and Functional Evaluation - a Health OUtcomes SurvEy) is a longitudinal research project designed to evaluate the impact of a personalized lifestyle, precision medicine intervention program.

 Speaker Profile

Ph.D., Population Health, Metabolon

Biography
Cindy builds partnerships with innovators to drive deep multi-omic phenotyping of multi-ethnic populations toward a future of real-time individualized healthcare. After completing her Ph.D. at UCSD, she joined Illumina as a Scientist where she founded their Consortia Program working in collaboration to build over 40 diverse array and sequencing-based tools in support of applications from psychiatric disease to advancing the global bovine dairy industry. She now leads population health initiatives in the western US for Metabolon. Cindy is an experienced consultant in the area of go-to-market strategy for startups and holds advisory board positions in several non-profits. She identifies strongly as a STEM mentor and coach for women in the sciences


Wellness & Aging Showcase:
Metabolon

Metabolon Inc is a health technology company advancing metabolomics for precision medicine for every area of life sciences research including applications in pharmaceutical research and development, clinical trials, nutrition, and consumer goods, and bioprocessing and cell culture science.

Metabolomics As A Functional Readout Of Wellness In The Context Of Polygenic Risk
Genetic insights have advanced our ability to stratify populations via polygenic risk. We discuss multi-omics and untargeted metabolomics as powerful tools to capture phenotype in the context of genetic risk. These tools guide researchers to advance preventative and individualized healthcare.

 Speaker Profile

M.D., CEO & Founder, Comite Precision Medicine & Health

Biography
Dr. Florence Comite is an internationally recognized leader and innovator in the field of Precision Medicine with extensive experience detecting, predicting, and reversing disorders of aging to optimize healthy longevity and vitality via personalized interventions. In 2005, Dr. Comite established the Center for Precision Medicine in New York City, where she integrates and interprets metabolomic, lifestyle, phenotypic and genomic data to provide n-of-1 health analyses and tailored interventions to high-level executives, physicians, celebrities, and self-quantifiers around the globe. Dr. Comite’s early-stage startup, Quantiome, scales her precise and personalized approach to health care as a digital application.


Wellness and Aging Showcase:
Comite Center

Comite Precision Medicine & Health (CPM&H) is a company with a mission to democratize access to n-of-1 health care. By integrating and interpreting an individual’s unique and evolving omics data, CMP&H provides tailored and proactive interventions that can reverse diseases of aging and optimize healthy longevity.

 Speaker Profile

M.D., Chief Medical Officer, JCVI

Biography
Dr. Pamila Brar is Chief Medical Officer and Clinical Phenotyping Research Lead at The J. Craig Venter Institute. In this capacity, she oversees the clinical aspects of a novel research effort that combines the power of genomics, metabolomics and microbiome with electronic medical records and artificial intelligence to identify markers of health and disease. From 2015 to 2018, Dr. Brar served as Medical Director of the Health Nucleus at Human Longevity, Inc, a precision medicine research clinic. In that role, Dr. Brar led a multidisciplinary team responsible for the integration of whole genome sequencing, microbiome, metabolome and whole-body imaging, as well as the delivery of results to the participants. Pam holds an MD degree from Louisiana State University at New Orleans. She is certified both by the American Board of Internal Medicine, and the American Board of Integrative Holistic Medicine. Dr. Brar is a graduate of the Scripps Clinic Internal Medicine Residency Program and was named the Ellen Browning Scripps Chief Medical Resident in 1998. She then joined the Division of Internal Medicine at Scripps Clinic where she practiced from 1999 to 2009. Pam then opened her own private concierge medicine practice in 2009 in La Jolla, CA. She served as President for the American Academy of Private Physicians from 2015 to 2017. Founded in 2003, the AAPP is a national non-profit organization that provides advocacy for the direct patient-doctor relationship and explores solutions to our changing health care system. Ultimately it was her love for science and innovation that led her to pivot from clinical practice to a precision-medicine based clinical research.


 Speaker Profile

Ph.D., CEO, Gero.AI

Biography
Peter was top-2 cited Russian physicist under 35 before he switched to biotech 15 years ago. In 2015, he co-founded Gero, AI-driven longevity startup focused on developing therapies that will extend a healthy human lifespan. He continues his studies in the field of aging biology and biophysics serving as Gero Chief Science Officer and currently has more than 70 papers published in peer-reviewed journals.


Wellness and Aging Showcase:
Gero.AI

Gero is an AI-driven drug discovery company focused on therapies targeting aging and age-related diseases.

GERO AI: Drug Discovery Against Complex Diseases
Gero has developed a platform for targets and biomarkers of aging identification. Recently Gero demonstrated outstanding results rejuvenating mice and extending their maximum lifespan in the lab of one of the top researchers in the field - Brian Kennedy.

 Speaker Profile

Head of Health Partnerships, 23andMe

Biography
Erin leads collaborations with digital health companies, provider organizations, and other healthcare players to advance 23andMe’s health product and strategy. A healthcare nerd with a passion for leveraging technology to solve the industry’s toughest problems, Erin has held a range of business development, corporate development, and product strategy roles at leading health tech companies including Redox, athenahealth, Doximity, and Rock Health. She holds a B.A. from the University of California, Berkeley and an MBA from Harvard Business School.


Wellness & Aging Showcase:
23andMe

23andMe, Inc. is the leading consumer genetics and research company. Founded in 2006, the mission of the company is to help people access, understand and benefit from the human genome.

23andMe: Turning Genetic Information Into Actionable Insights
The 23andMe cohort is the largest re-contactable research database of genotypic and phenotypic information in the world. By inviting customers to participate in research, we have created a new research model that accelerates genetic discovery and offers the potential to more quickly garner new insights into treatments for disease.