Session Abstract – PMWC 2024 Silicon Valley

Track 2 - January 24 9.00 A.M.-4.45 P.M.


Track Co-Chairs:
Russ Cucina, UCSF
John Kalafut, Asher Orion Group

  • PMWC 2024 Award Ceremony
    Luminary Honoree: Suchi Saria, Johns Hopkins
  • Integrated Diagnostics: The Future Powered by AI and Data Innovations
    - John Kalafut, Asher Orion Group
  • AI-Driven Integration of Genomic Data for Disease Understanding and Treatment
    - Mark Yandell, University of Utah
  • AI, Big Data and the Early Detection/Prevention of Chronic Diseases
    - Lee Hood, Phenome Health
  • Health IT and Interoperability Policy (PANEL)
    Chair: Russ Cucina, UCSF
    - Steven Lane, Gorila Health
    - Charles Jaffe, HL7
    - Alan Swenson, Sequoia Project
    - Neli de Crescenzo, Optum
    - Julia Adler, UCSF
  • Barriers and Challenges of Deploying AI into Clinical Use (PANEL)
    Chair: Ken Harris, AWS Global Medical
    - Bernardo Bizzo, Mass General Brigham
    - Suchi Saria, Johns Hopkins
    - Guido Matthews, Bayer
    - Tina Hernandez-Boussard, Stanford
  • Transforming Healthcare Using Big Data and Remote Monitoring
    - Michael Snyder, Stanford
  • AI-Powered Clinical Knowledgebases to Advance Precision Medicine Clinically
    Chair: Rakesh Nagarajan, Velsera
  • The Impact of AI and High Resolution Digital Slide Imaging on Clinical Practice
    Chair: Chris Coley, Epredia
  • AI Pathology's Horizon: Navigating the Future and Overcoming Obstacles (PANEL)
    Chair: Pavankumar Anne, ZS
    - Eric Walk, PathAI
    - Michael Rivers, Roche Diagnostics
  • PMWC Showcase
    - Elliott Green, Dandelion Health
    - Tomasz Jetka, Ardigen

 Session Chair Profile

M.D., Vice President, Genetics and Genomics, and Chief Medical Information Officer, UCSF Health

Biography
Dr Cucina is Vice President, Genetic and Genomic Services, and Chief Medical Information Officer, for the UCSF Health system. Working with the Chief Genomics Officer, he is responsible for the strategy and operations of UCSFs clinical genetic and genomics laboratories and services, and for the analytics, software, and information infrastructure to further the missions of UCSF Health. Dr. Cucina is board certified in Clinical Informatics and Internal Medicine, and practices in Hospital Medicine at UCSFs Parnassus Campus.


 Session Chair Profile

Head of Academic Medicine, AWS Global Medical

Biography
Ken leads the AWS Academic Medicine Vertical which includes a team of Principal Trusted Advisors in Digital Health, Hospital Modernization, Precision Medicine, Clinical Care, and Informatics, and HealthTech sub-verticals, and a team of field-based and customer-facing Healthcare Executive Advisors. He has over 30 years of healthcare experience, including founding and taking public a cell and gene therapy company. Prior experience includes being a Chief Clinical Officer, President, and CEO for 10 years prior to joining AWS. Ken has a strong background in building and commercializing regulated products in the device, combination product, clinical software, and therapeutic biologics space.


 Session Chair Profile

M.D., Ph.D., CMO, Velsera

Biography
Dr. Nagarajan has been a pioneer in genomics and informatics for 20+ years. He started at Washington University, the first CAP/CLIA laboratory for clinical NGS, and where he facilitated clinical and translational research by integrating EHR, clinical trials, patient registry, biospecimen, and genomics data and by supporting complex multimodal analyses across these data types. As the Founder and President of Pierian, he built the Clinical Genomics Workspace (CGW), an end-to-end disease, assay and instrument agnostic informatics solution used to process clinical NGS cases. At Velsera, Dr. Nagarajan leads the Knowledgebase team, which is responsible for curated clinical content that supports tertiary analysis in the CGW, and is responsible for regulatory submissions and for incubating and developing technology solutions to extend Velsera’s reach.


 Session Chair Profile

Global Marketing Development Manager, Digital Pathology, Epredia

Biography
Chris Coley, PA/HT(ASCP), has an extensive Anatomical Pathology background followed by various roles in sales and marketing for comprehensive product lines in the both clinical and research segments for over 25 years. His experiences enable him to implement market enhancing technologies that professionally align with Epredia’s mission and vision to improve lives by enhancing precision cancer diagnostics.


Talk
The Impact of Artificial Intelligence and High Resolution Digital Slide Imaging on Precision Medicine
Epredia hosts a partnership panel discussion on how 3DHISTECH acquired digital slide images are used with AI solutions from Aiforia and PaigeAI to drive accuracy and efficiency in the study and diagnosis of disease.


 Session Chair Profile

Ph.D., CSO & Co-Founder, Adaptive Biotech

Biography
Harlan Robins is a CoFounder of Adaptive Biotechnologies, a commercialstage biotech company that aims to translate the genetics of the adaptive immune system into clinical products to diagnose and treat disease. Prior to cofounding Adaptive, Harlan served in various roles at the Fred Hutchinson Cancer Research Center (FHCRC) in the Computational Biology Program, including Assistant Faculty Member, Associate, and Full Member and Head of the program.Interested in the mathematics behind genetics and observing the potential utility of highlevel mathematics to study problems in the biological sciences, Harlan took a postdoctoral appointment at the Institute for Advance Study in Princeton under famed biologist Dr. Arnold Levine. With Dr. Levine, he concentrated on developing bioinformatic algorithms for micro RNA targets and bacterial genome analysis, a precursor to his faculty appointment at FHCRC in the Computational Biology Group, Public Health Sciences and Human Biology Divisions.


 Speaker Profile

M.D., Ph.D., Senior Director, MGB Data Science Office, Instructor in Radiology, Harvard Medical School

Biography
Dr. Bizzo leads collaboration efforts with industry on AI product development and performance evaluation, including regulatory submissions, as well as clinical AI implementation with impact assessment and governance. Dr. Bizzo is a trained diagnostic radiologist with over 7 years of experience successfully overseeing the co-development of several AI-based products between MGB and industry collaborators. In 2020, he launched the MGB Digital CRO and has led the design and conduct of multiple clinical investigations to support successful FDA clearances of imaging-based AI products. He also created and runs the MGB AI Imaging Governance Committee to oversee the clinical implementation of AI solutions across MGB.


 Speaker Profile

Ph.D., Professor of Human Genetics, U. of Utah

Biography
Dr. Yandell is a Professor of Human Genetics, founding Director of the Utah Center for Genetic Discovery, and Chief Data Strategist for the University of Utah Hospitals program for Personalized Health. As such, he lead the institution's efforts to improve patient care using Whole Genome Sequences (WGS) and Electronic Health Records (EHRs). These efforts have been widely supported by the NIH and the American Heart Association, and have resulted in innovative techniques and software, including Artificial Intelligence (AI) applications. Now, in collaboration with Rady Children's Institute for Genomic Medicine and Fabric Genomics, they have developed GEM1, the first AI-based tool with the complete suite of features required for rapid, scalable diagnosis of critically ill children in the NICU and PICU. GEM is now integral to genome-based diagnosis programs at the University of Utah, at Rady Children's Hospital, and at the Broad Institute.


Talk
AI-Driven Integration of Genomic Data for Disease Understanding and Treatment


 Speaker Profile

Ph.D., Chair of Biomedical Data Science, Stanford

Biography
Sylvia Plevritis runs a research program that applies data science to the study of cancer systems biology and patient outcomes. She is focused on reverse engineering cell-cell interactions in the tumor micro-environment, from single cell sequencing and multiplexed imaging platforms, in order to identify biomarkers and drug targets and aid in treatment planning. She is a PI with the NCI Cancer Intervention Surveillance Network, an NCI consortium of investigators who use simulation modeling to improve our understanding of cancer control interventions in prevention, screening, and treatment and their effects on population trends in cancer incidence and mortality. These models have been used to guide public health research and priorities, and aid in the development of optimal cancer control strategies. She is a fellow of the American Institute for Medical and Biological Engineering and Distinguished Investigator in the Academy of Radiology Research, and serves on the NCI Board of Scientific Advisors.


 Speaker Profile

Ph.D., Co-Founder & CEO, Asher Orion Group

Biography
Dr. Kalafut advises on AIML topics ranging from product management to market strategy with a healthcare application. Additionally, he works with HCOs to develop AI strategies, AI Governance and best practices, through deployment and monitoring of purchased and built AIML solutions. He is the principal or coinventor on 43 US patents and 12 pending applications. Many of his inventions are used across nuclear medicine and radiological agent delivery, diagnosticinterventional cardiology devices, and patient monitoring systems. Before founding Asher Orion, John was Chief Scientist of Informatics Research at GE Healthcare. His stewardship of an AIenabled, diagnostic pathway solution led to their first Breakthrough Designation. He led the architecture of platforms and applications cocreated by GE Healthcare and its clinical partners at health systems, including Mass General Brigham and Boston Childrens Hospital. John contributed to the UKs National Consortium of Intelligent Medical Imaging (NCIMI) and was a coPrincipal Investigator on Digital Pathology and Diagnostic (DART).


 Speaker Profile

M.D., MPH, MPH, CMO, Health Gorilla

Biography
Steven Lane is a practicing primary care physician and clinical informaticist who currently serves as the Chief Medical Officer at Health Gorilla, a health data interoperability platform company supporting one of the first Qualified Health Information Networks (QHIN) as a component of the new federal Trusted Exchange Framework and Common Agreement (TEFCA) data exchange framework.Dr. Lane has more than 30 years of experience in clinical informatics and has worked on several initiatives related to the implementation and optimization of electronic health records (EHRs) and health health data interoperability. Dr. Lane is a recognized expert in the fields of health information exchange and data privacy.


 Speaker Profile

PMWC LUMINARY AWARD
Developed machine learning algorithms that improved critical care

Ph.D., Professor in Computer Science and Health Policy and Management, Johns Hopkins U.

Biography
Suchi Saria is a highly respected computer scientist and healthcare researcher who currently serves as the John C. Malone endowed chair and professor in the Departments of Computer Science, Medicine, Health Policy and Management at Johns Hopkins University. She is also the founding director of the Machine Learning, AI and Healthcare Lab at Johns Hopkins, where she leads a team of researchers dedicated to using machine learning and AI to improve healthcare outcomes.Professor Saria is known for her outstanding contributions to the precision medicine field through the development of AI algorithms and systems for clinical decisionmaking. Her work in predicting patient deterioration and providing personalized treatment recommendations has had a significant impact on patient care in critical care settings. For her contributions to the field of AI, machine learning and healthcare, Professor Saria has received various awards and honors.


 Speaker Profile

Executive Director, Carequality

Biography
As Executive Director of Carequality, Alan Swenson guides the development and implementation of the Carequality Interoperability Framework, the leading, nationwide trusted exchange framework enabling health data sharing across and among different types of networks and service providers. Alan also leads Carequality in supporting The Sequoia Project as the Office of the National Coordinator for Health ITs (ONCs) Trusted Exchange Framework and Common Agreement (TEFCA) Recognized Coordinating Entity (RCE). Alan has spent more than a decade focused on health IT interoperability. Before leading Carequality, he helped lead an exponential increase in patient record sharing through direct collaboration with hundreds of healthcare systems and provider organizations, EHR vendors, HIEs, HISPs, PHRs, payers, government agencies, and other digital health platforms. He has also volunteered with The Sequoia Project, National Association for the Support of LongTerm Care (NASL), CommonWell Health Alliance, DirectTrust, National Quality Forum, and HIMSS, among other industry interoperability initiatives.


 Speaker Profile

Ph.D., Professor in Computer Science and Health Policy and Management, Johns Hopkins U.

Biography
Suchi Saria is a highly respected computer scientist and healthcare researcher who currently serves as the John C. Malone endowed chair and professor in the Departments of Computer Science, Medicine, Health Policy and Management at Johns Hopkins University. She is also the founding director of the Machine Learning, AI and Healthcare Lab at Johns Hopkins, where she leads a team of researchers dedicated to using machine learning and AI to improve healthcare outcomes. Professor Saria is known for her outstanding contributions to the precision medicine field through the development of AI algorithms and systems for clinical decision-making. Her work in predicting patient deterioration and providing personalized treatment recommendations has had a significant impact on patient care in critical care settings. For her contributions to the field of AI, machine learning and healthcare, Professor Saria has received various awards and honors.


 Speaker Profile

Head Imaging, Data and AI Research Center of Excellence, Bayer

Biography
20+years of expertise working in healthcare and life sciences. Entrepreneur, digital transformation enthusiast and innovation leader to unlock personalized medicine and empower individualized patient care.


 Speaker Profile

Ph.D., Director of Data Science, Ardigen

Biography
Tomasz is a passionate mathematician turned data scientist, specializing in life sciences and biomedical applications. His research experience, ranging from wet lab experiments to rigorous theorems, has allowed him to push the boundaries of computational biology with novel discoveries in information theory.However, Tomasz's true calling was working at the forefront of AIdriven drug discovery. He has an impressive track record of successful projects in biology, bioinformatics, target identification, and drug repurposing, collaborating closely with pharmaceutical research scientists and internal programs. Tomasz specializes in extracting insights from large biological and biomedical datasets. He played a significant role in developing a comprehensive AI system for target identification, and was part of the preclinical team that delivered the first endtoend AI drug to the clinic.Currently, Tomasz leads the Data Science Center of Excellence at Ardigen, where he oversees and drives the company's data science and artificial intelligence initiatives.


Talk
Generalizing AI for populationscale healthcare datasets.
We delve into the broad applicability of machine learning for general population data and records. We will discuss the complexities of adapting AI models to diverse patient subgroups, mitigating biases, and ensuring the reliability and robustness of predictive algorithms that need to be implemented across multiple sites.


 Speaker Profile

Ph.D., Chair, Department of Genetics, Stanford

Biography
Dr. Snyder received his Ph.D. training at the California Institute of Technology and carried out postdoctoral training at Stanford University. He is a leader in the field of functional genomics and multiomics, and one of the major participants of the ENCODE project. His laboratory was the first to perform a largescale functional genomics project in any organism, and has developed many technologies in genomics and proteomics. Seminal findings from the Snyder laboratory include the discovery that much more of the human genome is transcribed and contains regulatory information than was previously appreciated (e.g. lncRNAs and TF binding sites), and a high diversity of transcription factor binding occurs both between and within species. He launched the field of personalized medicine by combining different stateoftheart omics technologies to perform the first longitudinal detailed integrative personal omics profile (iPOP) of a person, and his laboratory pioneered the use of wearables technologies (smart watches and continuous glucose monitoring) for precision health.


 Speaker Profile

Global Marketing Development Manager, Digital Pathology, Epredia

Biography
Chris Coley, PAHT(ASCP), has an extensive Anatomical Pathology background followed by various roles in sales and marketing for comprehensive product lines in the both clinical and research segments for over 25 years. His experiences enable him to implement market enhancing technologies that professionally align with Epredias mission and vision to improve lives by enhancing precision cancer diagnostics.


Talk
The Impact of Artificial Intelligence and High Resolution Digital Slide Imaging on Precision Medicine
Epredia hosts a partnership panel discussion on how 3DHISTECH acquired digital slide images are used with AI solutions from Aiforia and PaigeAI to drive accuracy and efficiency in the study and diagnosis of disease.


 Speaker Profile

Ph.D., MPH, MS, Associate Dean of Research, Stanford

Biography
Dr. HernandezBoussard is an Associate Dean of Research and Professor of Medicine (Biomedical Informatics), Biomedical Data Sciences, Surgery and Epidemiology Population Health (by courtesy) at Stanford University. With a rich background and vast expertise in biomedical informatics, health services research, and epidemiology, she is at the forefront of advancing healthcare through the development, evaluation and application of innovative methods. Through her research, she aims to effectively monitor, measure, and predict equitable healthcare outcomes. By leveraging diverse data sources, her team works diligently to construct a solid body of evidence that can significantly enhance patient outcomes, streamline healthcare delivery, and provide valuable guidance for health policy decisions. In addition, Dr. HernandezBoussard places significant emphasis on addressing bias and promoting fairness in AI for healthcare. Through her research and evaluation of AI technology, she seeks to advance healthcare practices while ensuring that diverse populations receive equitable resources, care, and outcomes.


 Speaker Profile

Ph.D., Professor in Computer Science and Health Policy and Management, Johns Hopkins U.

Biography
Suchi Saria is a highly respected computer scientist and healthcare researcher who currently serves as the John C. Malone endowed chair and professor in the Departments of Computer Science, Medicine, Health Policy and Management at Johns Hopkins University. She is also the founding director of the Machine Learning, AI and Healthcare Lab at Johns Hopkins, where she leads a team of researchers dedicated to using machine learning and AI to improve healthcare outcomes. Professor Saria is known for her outstanding contributions to the precision medicine field through the development of AI algorithms and systems for clinical decision-making. Her work in predicting patient deterioration and providing personalized treatment recommendations has had a significant impact on patient care in critical care settings. For her contributions to the field of AI, machine learning and healthcare, Professor Saria has received various awards and honors.


 Speaker Profile

MBA, CEO (former), Optum Insight

Biography
Neil de Crescenzo has been a CEO and Csuite executive leading some of the largest and most impactful organizations in the global healthcare information technology industry. Most recently, Neil was CEO of Optum Insight, one of the largest healthcare information technology organizations in the world with nearly $20 billion in revenue.Neil joined Optum through the acquisition of Change Healthcare in October 2022, where he served as president, chief executive officer, and a member of the Board of Directors. Change Healthcare was acquired by United Health Group for $13 billion.Before joining Change Healthcare, Neil was senior vice president and general manager of Oracle's Global Health Sciences business. Prior to joining Oracle, he spent a decade at IBM Corporation. Earlier in his career, he held leadership positions in a major hospital system, a large multispecialty group practice, and at a major health insurer.


 Speaker Profile

Ph.D., Chief, Division of Clinical Informatics & Digital Transformation, UCSF

Biography
Julia AdlerMilstein is a renowned health IT researcher at the University of California, San Francisco (UCSF). She is a Professor in the Department of Medicine, Chief of the Division of Clinical Informatics Digital Transformation, and Director of the Center for Clinical Informatics Improvement Research.Dr. AdlerMilstein's research focuses on the intersection of health information technology and healthcare delivery. She has conducted extensive work on the impact of EHRs and interoperability on clinical workflow, patient safety, and healthcare quality. Her research has been published in numerous highimpact journals, including the New England Journal of Medicine, Health Affairs, and JAMA.Dr. AdlerMilstein also serves as a consultant to federal and state agencies, including the Office of the National Coordinator for Health Information Technology and the California Department of Health Care Services. She is a member of the National Academy of Medicine and serves on the Board of the American Medical Informatics Association (AMIA).


 Speaker Profile

M.D., Ph.D., CEO and Founder, Phenome Health

Biography
Leroy (Lee) Hood, MD, PhD is the CEO Founder of Phenome Health, a nonprofit organization developing the Human Phenome Initiative, based on the science of wellness, which will sequence the genes and generate the longitudinal phenomes of one millionpeople over 10 years. Phenome Health is well positioned to deliver a new paradigm in healthcare based on prediction, prevention, personalization, and participation, and is intended to address several healthcare challenges: significantly improve health outcomes; facilitate brain health; increase cost effectiveness; reduce the chronic disease burden; promote healthy aging;and enhance U.S. leadership in medical innovation. He has co-founded 17 biotech companies including Amgen, Applied Biosystems, Rosetta and Arivale. His many national and international awards include the Lasker Prize, the Kyoto Prize, and the National Medal of Science.


 Speaker Profile

MBA, Partner and Precision Medicine Lead, ZS

Biography
Pavan is a Principal in the Boston office with a focus on Oncology and Precision Medicine. He co-leads ZS’ Biomarker Center of Excellence and works extensively with clients in the area of Precision Medicine. Over the last 12+ years at ZS, Pavan has focused on supporting Oncology companies across a full spectrum of medical, marketing and sales challenges. With experience working in most tumor types in Oncology, he brings deep therapeutic area expertise in Oncology. He has helped companies assess organization structures, develop commercialization strategy, segmentations, design forward looking local and global commercial models to successfully navigate the rapidly evolving Oncology market dynamics. With expertise in Precision Medicine and Oncology, Pavan has helped clients with market landscape and opportunity assessments, disease area strategy, and brand strategy including positioning. In addition, he has partnered with Oncology diagnostic companies across a range of engagements including portfolio strategy development, sales planning, customer segmentation, and competitive assessment. He holds an M.B.A from Yale School of Management, and B.S. in Mechanical Engineering from Indian Institute of Technology Madras. Prior to joining ZS, Pavan worked as a Design Engineer at Caterpillar Inc.


Talk
AI Pathology's Horizon: Navigating the Future and Overcoming Obstacles
This comprehensive 30minute session will address the rapidly evolving realm of AI Pathology and the critical challenges we face on the journey towards its full clinical adoption. Our discussion will not only highlight the exciting advancements but also the collaborative efforts required to surmount the barriers impeding progress.


 Speaker Profile

M.D., VP, Chief Health AI Officer and Associate CMIO for Inpatient Care, UCSF Health

Biography
Dr. Murray is a strategic health system leader for clinical informatics, digital health, and data science. She strives to leverage healthcare data in new and impactful ways to support improvements in quality, safety, and value for patients and providers. She has a focus on predictive analytics and artificial intelligence (AI) in healthcare, and her team has built infrastructure and governance processes to ensure deployment of ethical and robust AI. Her team evaluates commercially available tools and algorithms for trustworthiness prior to implementation and develops new machine learning models to address pressing health system problems. She is responsible for the overall strategy and vision for the use of AI to transform healthcare delivery at UCSF Health and beyond. She spends her clinical time caring for patients and teaching medical students and residents on the Hospital Medicine service at UCSF Health.


 Speaker Profile

M.D., FCAP, CMO, PathAI

Biography
Dr. Eric Walk is head of the PathAI Medical group, overseeing the PathAI Diagnostics pathology team. Eric has over 20 years of experience in precision medicine, oncology drug development and IVD companion diagnostics development. Prior to joining PathAI, he was Chief Medical and Scientific Officer at Roche Tissue DiagnosticsVentana Medical Systems, where he led Medical Scientific Affairs, overseeing the development and FDA clearanceapproval of over 20 510k and PMA IVD assays, companion diagnostics and digital pathology algorithms. Eric began his industry career at Novartis Oncology, where he held positions in Early Clinical Development and Translational Medicine. Eric is a Phi Beta Kappa graduate of Johns Hopkins University and holds a MD degree from the University of Virginia School of Medicine. He is board certified in Anatomic and Clinical Pathology and is a Fellow of the College of American Pathologists (CAP). He currently is a member of the CAP Digital Computational Pathology Committee.


 Speaker Profile

M.D., Ph.D., CEO, HL7

Biography
Charles Jaffe is the CEO of HL7 International. He completed his medical training at Johns Hopkins and Duke Universities and postdoctoral training at NIH and the Lombardi Cancer Center. He served in various academic positions in the Departments of Medicine and in the School of Engineering. Previously, he was the Senior Global Strategist at Intel, led a national research consortium, found a consultancy for research informatics, served as the VP of Medical Informatics at AstraZeneca, and the VP of Life Sciences at SAIC. He was the contributing editor for several journals and has published on clinical research, informatics, and healthcare policy.


 Speaker Profile

Vice President/Lifecycle Leader, Digital Pathology, Roche Diagnostics

Biography
Michael joined Roche Diagnostics in 2006 and has been Lifecycle Leader for Digital Pathology since October 2015. In this role, he leads the Digital Pathology team in Santa Clara, California to develop and commercialize the Digital Pathology portfolio of products and technology for Roche. Michael also is a Past President of the Digital Pathology Association and has been a member of the DPA Board of Directors since 2015. Michael has held a number of sales and marketing leadership roles at Roche and is passionate about the opportunity to transform cancer diagnostics with Digital Pathology.


×

Add Names/PO on Receipt

Apply to Speak at PMWC Silicon Valley by DEC. 14TH

The PMWC team will reply back to a suitable company/topic with an official request for talk/speaker details.

Contact Us:

Fields marked with an * are required 

Contact Us:

Fields marked with an * are required 

Discover What's Next in Precision Medicine!

Join our community today for the latest news, exclusive interviews, and unique insights from world-renowned speakers and experts


Contact Us:

Fields marked with an * are required 

Trouble Registering

Fields marked with an * are required

Stay Tuned For More Information.

Sign up for occasional updates on upcoming conferences, news, and other information. 

Get Updates:

Submit to Speak in the PMWC Showcase

Fields marked with an * are required