Speaker Profile

M.D., Ph.D., Professor of Pediatrics, Stanford University School of Medicine

Matthew Porteus is the Sutardja Clark Professor of Definitive and Curative Medicine in the Department of Pediatrics and Institute of Stem Cell Biology and Regenerative Medicine at Stanford. He is the co-Director for the Stanford Center for Definitive and Curative Medicine (CDCM). His primary research focus is on developing genome editing as an approach to cure disease, particularly those of the blood and immune system (including sickle cell disease) and other organ systems. His goal is to combine his research and clinical interests to develop innovative curative therapies. His dream is to one day develop gene editing so that patients are cured of their disease before they or their parents even knew they had it. He served on the 2017 National Academy Study Committee of Human Genome Editing and currently serves on the Scientific Advisory Board for WADA on Cell and Gene Doping and the NIH NExTRAC advisory committee evaluating the emergence of new technologies.

Genome Editing of Stem Cells
Genome editing provides unprecedented precision in developing personalized medicines for patients. By engineering cells ex vivo with high precision, it may be possible to generate cures for both rare and common diseases. I will discuss our progress towards this ambitious goal.

 Session Abstract – PMWC 2022 Silicon Valley

Track Chair:
Jane Grogan, Graphite Bio


  • Building Future Precision Care in Qatar
    Session Chair: Khalid Fakhro, Sidra Medicine
    - Barbro Friden, Sidra Medicine
    - Ziyad Hijazi, Sidra Medicine
    - Edison Liu, Jackson Labs
  • Advances in Gene & Cell Therapies
    Session Chair: Jane Grogan, Graphite Bio
    - Peter Nell, Mammoth
    - Laura Sepp-Lorenzino, Intellia Tx
    - Amy Simon, Beam Therapeutics
    - Eric Ostertag, Poseida Therapuetics
  • Translating CGT to the Clinic
    Session Chair: Nicole K. Paulk, UCSF
    - Matthew Porteus, Stanford
    - Eric Crombez, Ultragenyx Gene Therapy
    - Peter Francis, 4D Molecular Therapeutics
    - Erandi De Silva, Forge Biologics
    - Patrice Hugo, Q2 Solutions
  • Bioethics & Ethical Implications in Cell and Gene Therapies
    Session Chair: Ilana Yurkiewicz, Stanford University
  • Emerging Therapeutics Showcase
    - Yuri Fesko, Labcorp
  • Past, Present and Future of CRISPR Where will CRISPR Take Us and How is the Technology Evolving to Realize its Full Potential
    Session Chair: Janice Chen, Mammoth
    - Fyodor Urnov, UC Berkeley
    - Kiana Aran, Cardea Bio
    - Laura Sepp-Lorenzino, Intellia Tx
    - Josh Lehrer, Graphite Bio