Mark Smith is an emergency medicine physician who for the past 11 years has led a broad initiative to catalyze innovation in a large not-for-profit healthcare system, helping build centers in simulation training, human factors in healthcare, and telehealth innovation. He was co-creator of the Azyxxi/Amalga clinical information system which was in continuous use in hospitals for 22 years. Dr. Smith’s interests include digital health, advanced computational tools, complex systems theory, information visualization, disaster medicine, catalyzing sustainable and self-organizing change, and scaling that change within and across large systems of care. Prior to his appointment as director of the MedStar Institute for Innovation, Dr. Smith served as chair of the department of emergency medicine at MedStar Washington Hospital Center, Georgetown University School of Medicine, and at The George Washington University Hospital. He is a graduate of Swarthmore College (mathematics), Stanford University (computer science), and Yale University (medicine).