Speaker Profile

M.D., Personalized Hematology/Oncology of Wake Forest

Dr. Francisco Castillos is a Hematology/Oncology specialist in Wake Forest, NC and has been practicing for 20 years. He graduated from Chicago Medical School in 1995 and is board-certified in Internal Medicine, Oncology, and Hematology. He served with the 1st Marine Division for Alpha Surgical Company during Operation Iraqi Freedom, 1st FSSG, in 2003 as a Lieutenant Commander in the Navy. He is owner of Personalized Hematology/Oncology of Wake Forest, PLLC and focused on personalized medicine and efficient quality care. We utilize gene expression profiling to deliver optimal, safe, and cost-effective chemotherapy/molecularly targeted treatments, while ensuring that adult cancer patients are not under treated or over treated.

Using Personalized Medicine to Cure Metastatic Cancer
Used fresh tissue biopsies placed in RNA-later, mRNA extraction for high purity RNA, Affymetrix gene chip produced; used Pathway Studio (Elsevier) to analyze GEP, which provides molecularly targeted drugs to block the predominant signal transduction pathways for an individual’s cancer — stage IV patients remain in clinical remission using this approach.

 Session Abstract – PMWC 2020 Silicon Valley

Track 4, January 24, 4.15 P.M.

Dr. Yuryev introduces Elsevier biomedical knowledge graph and its applications for per-sonalized medicine. Dr. Castillos describes how Elsevier technology is integrated at WakeMed, including clinical paths, payment options, success rates based on five-year ex-perience in using affordable personalized drug therapy selection for advanced cancer pa-tients.