Speaker Profile

M.D., Director & CMO, Knight Diagnostic Laboratories, OHSU

Biography
Dr. Corless is Professor of Pathology at Oregon Health & Science University and serves as the executive director of the Knight Diagnostic Laboratories. His specialty is clinical implementation of new testing technologies for the molecular characterization of solid tumors.

Talk
Measuring Breast Cancer Biomarkers With The Nanostring GeoMx DSP
The Nanostring GeoMx Digital Spatial Profiler can generate tumor-specific quantitative readouts for over 90 protein and phospho-protein biomarkers using a multiplexed antibody approach. We developed a panel for measuring clinically informative biomarkers in samples of FFPE breast cancer and demonstrated its robust performance across multiple laboratories. The panel is ideal for analyzing clinical trial samples.


 Session Abstract – PMWC 2022 Silicon Valley


Track Chair:
Ira Mellman, Genentech

Human cells have been successfully used as treatment for blood cancers for decades but translating the promise to cell-based treatment for solid tumors has been slow. The advent of gene-editing techniques such as CRISPR, coupled with advances in our understanding of immunology and optimization of growing, manufacturing, transporting, storing, and handling specialized biological samples and materials is transforming the cell therapy field. We will hear in this session about some of the most promising work in the field, as well as the challenges in overcoming resistance

    Sessions:
  • Recent Advances in Cell-based Therapy (PANEL)
    Session Chair: Sascha Rutz, Genentech
    - Susie Jun, ArsenalBio
    - Elliot Norry, Adaptimmune
    - Tina Albertson, Lyell
    - Hy Levitsky, Century Therapeutics
  • Patentability of Immunotherapies—Latest Developments
    - Janet Xiao, Morrison & Foerster LLP
  • Cell-based Therapy Challenges (PANEL)
    Session Chair: Sharon Benzeno, Adaptive Biotechnologies
    - Arati Rao, PACT Pharma
    - Hy Levitsky, Century Therapeutics
    - Susie Jun, ArsenalBio
  • Next-generation Supply Chain For Cell & Gene Therapies (PANEL)
    Session Chair: Sharon Benzeno, Adaptive Biotechnologies
    - Tim Moore, Pact Pharma
    - Heidi Hunter, Cardinal Health
  • Advances in Multi-Omic Spatial Profiling
    Session Chair: Michael Rhodes, Nanostring
    - Chris Corless, OHSU
  • Biomarkers to Guide Immunotherapy
    Session Chair: Danny Wells, ImmunAI
    - Sanjeev Mariathasan, Genentech
    - Klaus Lindpaintner, InterVenn Bioscience
    - Lacey Padron, PICI
  • NaNots: A New Class of Immunotherapy
    - Lou Hawthorne, Nanotics
  • Engineered Therapeutics (PANEL)
    Session Chair: Paul Parren, Lava Therapeutics
    - Sonja Schrepfer, UCSF
    - Greg Lazar, Genentech