Speaker Profile

Ph.D., Ph.D., Assistant Professor -Engineering and Applied Science, Caltech (Jan 2023), William Hurt Scholar, Caltech/UCSD

Biography
Smruthi works on developing integrated wet-lab and computational biology techniques for studying microbial community dynamics in complex ecosystems. She is also the lead scientist in developing and implementing one of the largest SARS-CoV-2 wastewater surveillance programs. She was a GoMRI (Gulf of Mexico Research Initiative) scholar from 2016-2019. She won the 2018 James D Watkins student award for excellence in research instituted by the National Academies of Science, Engineering and Medicine and the ASM (American Society for Microbiology) Student award in 2019. She was selected as a 2019 MIT Rising Star in Civil and Environmental Engineering. She was also chosen as one of ten Rising Stars in Science by Science News SN10 in 2022. Her research has been highlighted on CBS 60 minutes, TIME Magazine, Forbes, NBC Nightly News, Reuters, The New York Times, CNN, The Scientist, Nature, The Conversation, FiveThrityEight, JAMA amongst others.

Talk
Seer in the Sewer: Wastewater sequencing for public health


 Session Abstract – PMWC 2023 Silicon Valley

Track 3 - January 27 9.00 A.M.-4.15 P.M.


Track Chairs:
Sharon Terry, Genetic Alliance & Alice Rathjen

  • PMWC 2023 Award Ceremony:
    Pioneer Honoree: David Bentley, Ilumina
  • Learnings and Advancements of Population Studies
    Chair: Sharon Terry, Genetic Alliance
    - David Bentley, Ilumina
    - Slavé Petrovski, AstraZeneca
    - Andrea Ganna, FinnGen
    - Alexander Charney, Mount Sinai
  • Precision Medicine in Understudied Populations
    - Ryan Taft, Illumina
    - Aimé LUMAKA, WALGEMED
  • Building Future Precision Care in Qatar
    Chair: Khalid Fakhro, Sidra Medicine
    - Ziyad M. Hijazi, Sidra Medicine
    - Edison T. Liu, The Jackson Labs
  • Challenges and Opportunities for National Precision Medicine Initiatives (PANEL)
    Chair: Alessandro Ricommbeni, Microsoft UK
    - Catalina Lopez-Correa, Genome Canada
    - Khalid Fakhro, Sidra Medicine
  • Framework to Improve the Translation of Genomics into the Clinic (PANEL)
    Chair: Kathleen Barnes, Tempus Labs
    - Carlos Bustamante, Galatea Bio
    - Ora Gordon, Providence
    - Abasi Ene-Obong, 54gene
  • Identifying Relationships Between Disparate Data Sets to Monitor and Control Pathogen Outbreak (PANEL)
    Chair: Charles Chiu, UCSF
    - Amy Kirby, CDC
    - Smruthi Karthikeyan, UCSD
  • Increasing Diversity in Population Studies
    - Manual Rivas - Global Biobank Engine, Stanford Rivas Lab
  • The Missing Diversity in Human Epigenomic Studies
    - Charles E. Breeze, National Cancer Institute
  • The Transition from Genomics to Phenomics in Precision Population Health
    - Lee Hood, Phenome Health

 Session Abstract – PMWC 2023 Silicon Valley

Track 3 - January 27 9.00 A.M.-4.15 P.M.


New efforts that are currently underway are attempting to leverage waste water surveillance data to monitor status and predict near term direction of pathogen outbreaks via linking it to patient data based on hospital observations. The overall goal is to identify potential pathogens, the related infection status in the population, and to possibly even predict resurgence of a previously identified pathogen via comparison of sequencing data from hundreds of patients to pathogen detection in a broad sampling of waste water across a given area. This panel which includes public health officers, epidemiologists, and research scientists will focus their debate of this timely subject on what promise and predictive value this approach may hold.