Speaker Profile
Ph.D., HCLD, Cofounder, CSO, and Clinical Laboratory Director, Genomic Prediction
Biography
Nathan Robert Treff is the recipient of 8 Prize Paper Awards, and the 2013 New Investigator Award from ASRM. He has published over 120 peer reviewed papers in Reproductive Genetics and serves as a member of the ASRM Research Committee, and Senior Associate Editor of JARG, and Editor of Fertility and Sterility. He holds a PhD in Biochemistry from Washington State University and an HCLD in Molecular Diagnostics from ABB.
Talk
Reducing polygenic disease risk through embryo selection
Current IVF practice involves selecting embryos for transfer based upon their appearance under a microscope. Contemporary genetic testing provides a new opportunity to prioritize embryos with the lowest risk of developing polygenic disease. This presentation will address several misconceptions surrounding the validity and ethics of polygenic risk scoring for embryo selection.
Session Abstract – PMWC 2023 Silicon Valley
Track Co-Chairs:
Linda Giudice, UCSF
Yoel Sadovsky, UPMC
Researchers have long been recognizing the uniqueness of women’s health and its substantial effect on clinical practice, acknowledging the increasing appreciation of the importance of multidisciplinary approaches to health and disease. In every organ system, there are diseases that are unique to women, more common in women than in men, or characterized by differences in disease course in women compared to men. This Track will focus on the following topics related to Women’s Health:
- PMWC 2023 Award Ceremony:
Pioneer Honoree: Marcia Stefanick, Stanford - Chronic Diseases in Women
- Marcia Stefanick, Stanford (Chronic Disease Prevention) - Marina Sirota, UCSF (Endometriosis) - Stem Cells, Preimplantation and Prenatal Genetics
Chair: Akash Kumar, MyOme, Inc. (Ploygenic risk score)
- Teresa Sparks, UCSF (Prenatal genetic diagnosis)
- Nathan Treff, Genomic Prediction (Reducing polygenic disease risk through embryo selection)
- Precision Health for Mothers and Babies
Chair: David Stevenson, U. of Stanford (Introduction: Towards Precision Health for Mothers and Babies)
- Aleks Rajkovic, UCSF (Genomics of Pregnancy Loss)
- Ivana Maric, Stanford (ML for Early Prediction)
- Nima Aghaeepour, Stanford (AI-Driven Prematurity Taxonomy)
- Precision Health for Mothers and Babies: Components of Pregnancy Health
Chair: Yoel Sadovsky, U. of Pittsburgh (Placental Health)
- Marina Sirota, UCSF (Leveraging Molecular and Clinical Data)
- Brice Gaudilliere, Stanford (Multiomic immune profiling) - Value of Early Risk Prediction, Screening & Digital Intervention in Pre-term birth Avoidance
Chair: Leslie Saltzman, Ovia Health
- Sydney Strickland, Labcorp - Reproductive Aging (PANEL)
Chair: Aleksandar Rajkovic, UCSF
- Diana Laird, UCSF
- Jennifer Garrison, Buck Institute
- Nikolina Lauc, GlycanAge
- Christian Kramme, Gameto - Achieving Equity in Precision Medicine
- Aida Habtezion, Pfizer - Sex Differences
- Noel Bairey Merz, Cedar Sinai (CV disease)
- Danit Ariel, Stanford (Transgender Health and Sex Differences)
- PMWC Showcase:
- Amrie Grammer, Ampel Bio Solutions
