Speaker Profile

Ph.D., Professor of Genetics, University of Newcastle

Professor Cairns is using systems biology in complex disorders to improve our understanding and identify novel opportunities for treatment. In recent work he has focused on individualized analysis of both genomic and transcriptomic variation to identify opportunities for drug repositioning and precision intervention. He is an NHMRC Senior Research Fellow at the University of Newcastle, Australia. He received his PhD in Biochemistry and Molecular Genetics from the University of New South Wales, Sydney Australia. Professor Cairns was an industry postdoctoral fellow at Johnson and Johnson Research and Nucleics before moving to academic research. Professor Cairns has authored more than 130 publications in various journals and books. His publications reflect his research interests in genomics, bioinformatics, systems biology, pharmacology and precision medicine.

Genomic Profiling Showcase:
University of Newcastle

The University of Newcastle and Hunter Medical Research Institute are highly regarded for health related training, research and clinical translation.

Precision Medicine For Individuals With Complex Disorders Through Pharmacological Annotation Of Their Polygenic Risk
In this talk I will present our informatics framework for quantifying an individual’s common variant enrichment (of complex disorder-associated polygenic risk) in clinically actionable systems. This approach, designated pharmagenic enrichment, facilitates precision medicine by pharmacological annotation of polygenic risk.

 Session Abstract – PMWC 2020 Silicon Valley

The PMWC 2020 Genomic Profiling Showcase will provide a 15 min speaking opportunity for selected companies working with the latest technologies in nucleic acid sequencing such as NGS, providing instrumentation for genomic sequencing, and offering direct to consumer services. These companies will share their innovative products and services to an audience of leading investors, potential clients and partners. The Genomic Profiling Showcase will exhibit the latest innovations in methods and instruments used for DNA/ RNA sequencing to ascertain the genomic and transcriptional profile of a person in order to understand why some people get certain diseases while others do not, or why people react in different ways to the same drug. This information is also being used to develop new ways to diagnose, treat, and prevent diseases, such as cancer.