Dr. Tsimberidou has designed highly innovative clinical trials that have changed the standard of practice of oncology in patients with solid tumors and hematologic malignancies. She pioneered the personalized medicine program for advanced cancer at MD Anderson Cancer Center, demonstrating that identification of molecular aberrations and selection of therapy based on tumor abnormalities is associated with improved clinical outcomes compared with standard approaches. She is leading IMPACT2, a randomized trial in precision oncology, and personalized immunotherapy trials. She has published >280 articles in high-impact peer-reviewed journals. She has been invited to present her work as a keynote speaker at numerous national and international conferences. She has received various prestigious awards including a Career Development Award from ASCO. She chaired ASCO’s Clinical Research Committee (2016-2017) and serves on various ASCO committees. Her high-quality innovative research focuses on development and implementation of precision oncology through innovative therapeutic approaches, education, and patient care.
Implementation of Precision Oncology in Advanced Cancer
In 2007, we initiated the personalized medicine program for patients with advanced cancer. We used tumor molecular profiling to optimize selection of investigational targeted therapies and demonstrated that this approach was associated with favorable outcomes. Although several gaps still exist, personalized oncology holds the promise to improve clinical outcomes.
Track Chair: Cindy Perettie, Roche