Adrian Hill and his research group have designed, manufactured and developed many new vaccines for malaria, exploring a range of vaccine technologies that have informed progress for vaccine design against many diseases. His current lead malaria vaccine has shown high efficacy in clinical trials in the UK and Africa and is likely to be the first widely used vaccine to impact on the great disease burden of malaria in Africa. In 2005 he founded the Jenner Institute at Oxford, an initiative aimed at accelerating public sector vaccine development for a range of infectious diseases, and partnered with the Pirbright Institute on veterinary vaccine development. The Jenner Institute is now the largest academic vaccine centre globally with clinical-stage vaccine programmes against thirteen diseases. Recently the Jenner Institute has initiated a major effort towards rapid development of a COVID-19 vaccine. A clinical trial of which he is the Oxford principal investigator has started recently. He has published 600 research papers with over 68,000 citations and co-founded several vaccine companies.