Session Abstract – PMWC 2022 Silicon Valley


The PMWC 2022 Wellness & Aging Showcase will provide a 15-minute time slot for selected companies in Wellness and Aging to present their latest technologies to an audience of leading investors, potential clients, and partners. We will hear from selected companies that build innovative solutions and harness the power of digital health, genomics, and data science with the goal to proactively prevent disease, maintain optimal health, and slow down aging.


Confirmed Presenting Companies:

 Speaker Profile

Ph.D., Head of Science, Seven.me

Biography
Dr. Jennifer Lovejoy is a senior executive and biobehavioral scientist with deep experience in personalized medicine. During her academic career, Dr. Lovejoy held the Manship Endowed Professorship in Diabetes at LSU's Pennington Biomedical Research Center. She is a Past-President of the Obesity Society and has published over 80 peer-reviewed papers on her research. More recently, Dr. Lovejoy was Chief Translational Science Officer at Arivale, a precision medicine startup uniting systems biology and behavioral science to help consumers optimize wellness. Currently, she works at Seven.me, a digital health startup developing a unique behavioral AI platform combined with coaching and rapid at-home blood testing to help consumers transform their health.


 Speaker Profile

M.D., Ph.D., Professor, University of Washington

Biography
The focus of Dr. Rabinovitch’s research is on the use of mouse models to examine the effects of modulating mitochondrial function on lifespan and healthspan. Transgenic mice that express catalase in mitochondria, as well as the tetrapeptide SS-31 (elamipretide) have been found to be protected against multiple health challenges, including cardiac aging and sarcopenia. His work tests the hypothesis that acute enhancement of mitochondrial function is followed by persistent structural, proteomic and metabolic remodeling that improves aged physiological performance. Studies of proteomic abundance, turnover and post-translational modification have been invaluable tools in this work. Dr. Rabinovitch is a Fellow of the AAAS, past recipient of the Denham Harmon Research Award from the American Aging Association, an Ellison Medical Foundation Senior Scholar in Aging grant award, and a Breakthroughs in Gerontology grant award from the American Federation for Aging Research.

Talk
Interventions To Enhance Aging Muscle Mitochondrial Function
Treatment with the mitochondrial targeted peptide SS-31 (elamipretide) or late-life viral expression of mitochondrial-targeted catalase (mCAT) can substantially reverse cardiac dysfunction and reduced endurance of old mice. These results implicate mitochondrial energetics and redox signaling as therapeutic targets for muscle aging.


 Speaker Profile

M.D., Chief Hematology/Oncology, LifeOmic; Med. Research Scientist, IU Health

Biography
Jamie earned her BS in chemistry from the University of Rochester and a MD from St. Louis University School of Medicine, where she also completed her pediatrics residency training. She then went on to Baylor College of Medicine/Texas Children’s Cancer Center in Houston to complete pediatric hematology/oncology fellowship training. She relocated to Indianapolis after completion of her training to join the faculty at Indiana University School of Medicine (IUSM) where she also earned a master’s degree in clinical research as part of the Clinical Investigator Training Enhancement Program. Jamie is the Caroline Symmes Professor of Pediatrics and Division Chief of Pediatric Hematology/Oncology at IUSM.


Wellness & Aging Showcase:
LifeOmic

LifeOmic is the software company that is activating the future of healthcare from wellness and prevention-oriented LIFE mobile apps with over 3.5 million users worldwide to a precision medicine platform that enables cancer researchers to develop novel and effective treatments for the most aggressive cancers.

Harnessing Oncology Research to Inform Individual Wellness
How can pediatric oncology influence individual wellness? Dr. Renberger will unveil her newest venture as an expert in the LIFE Ascent program from LifeOmic, created by physicians and scientists to guide individuals on creating habits scientifically proven to combat aging and chronic disease.