Session Abstract – PMWC 2020 Silicon Valley


Considering the differences between males and females in clinical decision-making is crucial. However, white adult men are strongly over-represented in existing medical data sets as clinical trials have not adequately enrolled women or analyzed sex-specific differences in the data. This lack of diversity in the data results in inaccurate treatment decisions. These same limitations are the result of the current “reference genomes” which are predominantly based on white, European ancestry. To fulfill the promise of precision medicine, clinical trials and population studies need to adequately include the female sex. This session will review the needs and progress being made to correct this issue so precision medicine can become more precise.

 Session Chair Profile

M.D., Ph.D., Founder and Managing Director, EXXclaim Capital

Biography
Anula Jayasuriya is a private equity executive and venture capitalist. She founded EXXclaim Capital, an early stage venture fund focused on catalyzing innovation, entrepreneurship and investment in Women’s Health. Anula co-founded the “Evolvence India Life Science Fund”, the first fund in India to focus on health care and invest in Indian pharmaceutical, biotechnology, medical device and contract services companies. She was a partner with Skyline Ventures in Palo Alto, and with the German/US venture capital firm TVM, in San Francisco. Her prior positions include VP Business Development at Genomics Collaborative Inc., and Vice President, Global Drug Development at Hoffman-La Roche for opportunistic infections in AIDS and Transplantation. Anula received a BA from Harvard, and an MD and PhD in Microbiology and Molecular Genetics from Harvard Medical School and an MBA from Harvard Business School, as well as a M. Phil. in pharmacology from the University of Cambridge, in England.


 Speaker Profile

DO, FACC, FAHA, President, SRSHeart. Inc,.; National Spokesperson, Go Red for Women, American Heart Association

Biography
Dr. Suzanne Steinbaum is an attending cardiologist, specializing in prevention. She recently was the Director of Women's Cardiovascular Prevention, Health and Wellness at Mt. Sinai Heart in New York City, after being the Director of Women’s Heart Health at Northwell Lenox Hill. She is the author of Dr. Suzanne Steinbaum’s Heart Book: Every Woman’s Guide to a Heart Healthy Life, and Lower Your Blood Pressure Naturally, with the editors of Prevention. She has been awarded a New York Times Super Doctor, a Castle and Connolly Top Doctor for Cardiovascular Disease and New York Magazine’s prestigious Best Doctors in the New York edition.


 Speaker Profile

M.D., Executive Director, Connors Center for Women’s Health and Gender Biology, Brigham & Women’s Hospital, Harvard Medical School

Biography
At Brigham/Harvard Connors Center for Women’s Health and Gender Biology, Dr. Joffe is launching the First-in-Women Precision Medicine Platform to advance knowledge about novel therapeutics across therapeutic areas for diseases that affect women exclusively, predominately, or differentially. First-in-Women is engaging with academics and biopharma to generate new scientific knowledge and educate across the biomedical ecosystem to optimize care for women. In her own research, she is an experienced clinical reproductive neuroscientist in the field of women’s aging and mental health. She focuses on the mechanisms, course, and treatment of menopause-related symptoms (hot flashes, insomnia, depression, and fatigue) in healthy midlife women and breast cancer survivors. Dr. Joffe holds an AB from Harvard University, an MD from Cornell University Medical College, and an MSc from Harvard School of Public Health. She completed her residency in Psychiatry at McLean Hospital and Women’s Mental Health fellowship at Massachusetts General Hospital.


 Speaker Profile

Ph.D., Professor of Medicine, Stanford University

Biography
Dr. Stefanick's research, which has been widely disseminated nationally and internationally, has emphasized the role of lifestyle—especially exercise, diet, weight control, and menopausal hormone therapy—on chronic disease prevention, particularly heart disease, breast cancer, osteoporosis, and more recently, dementia. Her primary academic interests include sex/gender differences and the influence of sex hormones on human physiology and disease, menopause, and health promotion over the life course, including healthy aging. She offers courses on these subjects at Stanford, where she plays major leadership roles in the Women's Health at Stanford program, the Cardiovascular Institute's Women's Heart Health Program, and the Cancer Prevention and Control Program of the Stanford Cancer Center.


 Speaker Profile

M.D., Associate Professor of Medicine, UCSF

Biography
Dr. Parikh is an Associate Professor of Medicine in the Division of Cardiology at UCSF. She did her internal medicine training at Tufts Medical Center, her cardiology training at Harvard Beth Israel Deaconess Medical Center and an MPH at UC Berkeley. In her cardiology practice, she emphasizes primary and secondary cardiovascular disease prevention. She studies women & cardiovascular diseases across the lifespan; including cardiovascular disease in pregnancy and the post-partum period. Her research leverages data from Women's Health Initiative Study, statewide insurance claims databases and the Swedish Population Registers. She currently serves on the AHA Leadership Committee of the Epidemiology and Prevention Council. She has published over 60 peer reviewed papers and has an active NIH-funded research program. Dr. Parikh founded and currently co-leads the Women in Cardiology (WIC) Council at UCSF, which promotes the entry of women into cardiology and pursues gender equity in cardiology fellowship recruitment.