Biography
As Head of Oxford Nanopore Diagnostics (OND), Emma supports Oxford Nanopores ambitions for growth in healthcare applications.Until November 2020, Emma was Director for Supplies and Innovation as part of the British governments NHS Test and Trace response to COVID19. Prior to this, Emma was CEO of Four Eyes Insight, Chief Partnership Officer for Beacon Health Options (Northeast USA) and CEO of Beacon in the UK. Emma has also been a Commonwealth Fund Harkness Fellow in Healthcare Policy and Practice and a Senior Associate at the Institute for Strategy and Competitiveness, both at Harvard University. Prior to this, Emma was a practicing clinician in the UKs National Health Service (NHS).

Biography
Stacey Gabriel is a human geneticist with a research interest in largescale genomics research. The organization that she leads operates as one of the largest sequencing centers in the world and continually explores, validates, optimizes, and implements new technologies, methods, and analysis tools to meet the needs of the scientific community. She has played a central role in the development of methods for generating and analyzing data using genomic technologies for both cancer and medical genetics studies. Her research on the haplotype structure of the human genome provided foundation for the Human HapMap Project. She directs the Broad Institutes execution in flagship largescale projects including the Human HapMap, the 1000 Genomes Project, The Cancer Genome Atlas, and the All of Us Research Program. During the covid19 pandemic Dr. Gabriel led the development and execution of a commercialscale diagnostic testing and viral surveillance activity.

Biography
Dr. Robert Sebra is the founding Director of the Center for Advanced Genomics Technology (CAGT) which is focused on accelerating innovation and commercial platform application to ensure that the scientific and medical communities have access to a broad toolbox to enable technologydriven omics research. Dr. Sebra has built a unique technology development program that focuses on cutting edge single molecule, bulk, single cell, and spatial multiomics molecular and analytical methods development for community application and datasets for translational science and medicine research with over 200 publications and patents, to date. His research program focuses on applying these technologies to study development, tumor progression, and infectious disease to better characterize health and disease progression. Recent research interests include discovery of biomarkers of tumor initiation, novel gene discovery in human preimplantation development, and engineering of accelerated AI foundation models to facilitate cellular and gene expression signatures of disease.

Talk
Improving transcriptomics data interpretability via single-cell informed machine learning
This talk will cover the integration of single-cell data from 1500 studies via Unicell Deconvolve. Well delve into the future implications of single-cell and spatial data, presenting a universal model applicable to all human systems. The focus centers on interpretable machine learning approaches to reveal cellular and transcriptional signatures affecting patient outcomes.

Biography
Dr. Prashant Kumar brings along with him vast expertise accomplishments in the field of Cancer Biology and has done extensive research to enhance the translational merits of cancer research. He worked in several pathbreaking research initiatives that includes establishing a novel mouse model of malignant breast cancers, optimization of a culture method to assess CTCs, implementation of cuttingedge technologies in genomics, proteomics to investigate biomarkers and therapeutic targets to accelerated discovery in the advancement towards cancer vaccines, precision medicine, molecular diagnostics.Dr. Kumar received his Ph.D. in 2009 from the Max Planck Institute for Infection Biology, Berlin, Germany. Following this, he did his postdoctoral work at the Department of Cancer Biology, UMASS, Worcester, USA. To further advance his research stint, he joined Prof. JeanPaul Thiery, a world renowned authority in the area of EMT at IMCB, ASTAR Singapore. Currently he is the Chief Scientific Officer (CSO) of Karkinos Healthcare.

Biography
Heidi Rehm is a renowned human geneticist and genomic medicine researcher who has made significant contributions to the field of genomics including developing and implementing new approaches, standards and resources to improve genetic testing and diagnosis for rare diseases. She holds several prominent positions including a chief genomics officer role to apply genomics to clinical care across MGH. She is also the codirector of the Program in Medical and Population Genetics at the Broad Institute of MIT and Harvard, where she coleads several initiatives to advance genomic medicine research including the Broad Center for Mendelian Genomics involved in rare disease gene discovery, as well as the Clinical Genome Resource (ClinGen) and Genome Aggregation Database (gnomAD), providing free and publicly accessible resources to support the interpretation of genes and variants. She is the recipient of the Curt Stern Award from the American Society of Human Genetics and has published over 250 peerreviewed papers.

Biography
Walt is passionate about making a difference for patients. He spends his days focused on areas where genetics and genomics bring new insight into disease biology. Walt works where science meets business and strategy, enabling insights from the lab to become the next generation of medicines that can change lives. He is enthusiastic about launching companies with emphatic, truly patient centric cultures that effectively and efficiently execute drug discovery. He places priority on taking the time to listen to the patients whom we endeavor to help, recognizing that the value we aim to create is defined by the difference we can make in their lives. Walts greatest accomplishment is that his three children are eager learners and kind to one another, their family, and their classmates.

Biography
Cindy is passionate about innovation to make genetic and multiomic technologies easier and cheaper to measure. She sees such innovation as pivotal to lower the barrier of entry for implementing scalable, reproducible solutions advancing individualized medicine and health equity. In over 14 years at Illumina and together with customers, she helped develop solutions to advance the understanding of genetic risk and holds several USDA Excellence in Technology Transfer awards for her work leading Illuminas Consortia Program. She joined Olink in 2020 soon after the launch of the Explore Platform that leverages next generation sequencing as a high throughput proteomic readout. Ask her about how high throughput proteomics are helping translate the impact our genetics has on more real time health.

Biography
Dr. Gaziano, Professor of Medicine at Harvard Medical School, is a prominent chronic disease epidemiologist and trialist with a focus on the study of chronic diseases, particularly the influences of lifestyle choices, metabolic factors, and biochemical and genetic markers on coronary artery disease and stroke. He is the Executive Director of the Massachusetts Veterans Epidemiology Research and Information Center (MAVERIC) at the VA Boston Healthcare System. He is one of the PI for the Million Veteran Program (MVP), an observational cohort with stored biospecimens. Enrollment currently stands at 980,000 veterans and is quickly approaching its target of 1,000,000 enrollees. He also serves as the Chief of the Division of Aging at Brigham and Women's Hospital, where he is the PI of the Physicians Health Study, a largescale trial exploring the role of vitamins in preventing chronic diseases. He has a prolific publication record with over 750 original reports, reviews, and book chapters.

Biography
Charles Chiu, M.D.Ph.D. is a Professor at UCSF, Director of the UCSFAbbott Viral Diagnostics and Discovery Center (VDDC), and Associate Director of the UCSF Clinical Microbiology Laboratory. Chiu currently leads a translational research laboratory focused on clinical metagenomic sequencing assay development for infectious diseases and genomic investigation and surveillance of emerging pathogens, including the SARSCoV2 coronavirus. He also uses RNASeq transcriptome profiling to develop predictive models using machine learning for host responsebased diagnosis of COVID19 and other infections. Chius work is supported by funding from the National Institutes of Health (NIH), Department of Defense, US Centers for Disease Control and Prevention (CDC), philanthropy, and the California Initiative to Advance Precision Medicine. He has authored more than 100 peerreviewed publications (20 on COVID19), holds over 15 patents and patent applications, and serves on the scientific advisory board for Mammoth Biosciences, Danaher Dx, Biomesense, and Flightpath.

Biography
Dr. Xie possesses a distinct expertise in the development and commercialization of innovative instruments for microcolumn separations in lifescience research. During his doctoral work under Prof. Milton Lee, two of his projects resulted in patented innovations that were subsequently commercialized. Later, he became a key member of the startup Axcend Technologies, where he played a pivotal role in commercializing fieldportable liquid chromatography tools he had a hand in developing. In 2021, he partnered with Ryan Kelly's laboratory as a postdoctoral research associate. By 2022, he ascended to the position of Manager at MicrOmics Technologies. In this capacity, he made significant strides in the creation of robotic platforms for singlecell proteomics and pioneering the nextgeneration LCMS platform tailored for singlecell proteomics.

NCI Showcase:
MicrOmics Technologies
MicrOmics Technologies LLC was founded to make advanced technologies available to scientists seeking to extend the capabilities of their LC-MS workflow, particularly for increased sensitivity and analysis of smaller samples (e.g., single-cell proteomics).

Biography
Bill is a respected expert in both basic research and clinical lab technology development as faculty in UCSF Laboratory Medicine and Venture Partner at Genoa Ventures. Academically, Bill directed several labs with a strong concentration on cytometry and genomic technologies implementing a myriad of research, translational and clinical applications. His career includes joint appointments at UC Berkeley and LBNL, three honorary doctorates, and authorship of over 100 peerreviewed publications. Bill has been directly involved in the conception, engineering, and validation of more than 20 commercially successful analytical instruments, consumable products, and software programs, often in collaboration with strategic partners like Zeiss, Danaher, Thermo, BD, and Sony. Bill is an investor, andor advisor to more than 50 companies, cofounder of 11 startups, shepherding 14 exits. Bill joined Genoa Ventures at its inception to invest in unique opportunities and to further capitalize on his ability to repeatedly identify disruptive science in transformative markets.

Biography
Dr. Turner founded PacBio in 2004. He was awarded a Ph.D. in Physics by Cornell University in 2000, where he worked with Prof. Harold Craighead to study the behavior of biomolecules in nanofabricated structures. He was a member of the project team at Cornell which developed the technology now employed by PacBio and was coauthor of the cover story in Science magazine (13103) that introduced the technology to the scientific community. Dr. Turners undergraduate work was at the University of Wisconsin, Madison, where he received a B.S. in Applied Mathematics, Electrical Engineering and Physics. He is the author of over 50 scientific papers in fields ranging from DNA sequencing technology and biophysics to genomics and epigenomics. He is listed as the inventor on over 50 U.S. patents and numerous published patent applications. Dr. Turner was recipient of the MIT Technology Review TR100 Award in 2003 and the UWMadison Distinguished Young Alumnus Award in 2008.

Biography
Anshul Kundaje's primary research area is largescale computational regulatory genomics. The Kundaje lab specializes in developing statistical and machine learning methods for largescale integrative analysis of heterogeneous, highthroughput functional genomic and genetic data to decipher regulatory elements and longrange regulatory interactions, learn predictive regulatory network models across individuals, celltypes and species and improve detection and interpretation of natural and diseaseassociated genetic variation. Previously as a postdoc at Stanford and Research Scientist at MIT, Anshul was the lead computational analyst of the ENCODE Project and the Roadmap Epigenomics Project. Anshul is also a recipient of the 2016 NIH Director's New Innovator Award and the 2014 Alfred Sloan Fellowship.

Talk
Deep learning regulatory sequence syntax and variation

Biography
Dr. Chaz Langelier is an Associate Professor of Medicine in the Division of Infectious Diseases at UCSF. His work seeks to advance the understanding and management of pneumonia, sepsis, and other infectious and inflammatory diseases. His laboratory combines host gene expression profiling, metagenomic pathogen detection and profiling of the microbiome to develop novel molecular diagnostics, study hostpathogen biology, and advance methods for emerging infectious diseases surveillance.

Talk
Integrated HostMicrobe Metagenomics for Diagnosis of Sepsis and Pneumonia
Combining host transcriptional profiling and unbiased microbial metagenomics affords accurate diagnosis and detection of probable pathogens in critically ill patients with sepsis and pneumonia.

Biography
Dr Vishal Gulati is a venture capitalist investing globally in companies applying Moore's Law-based technologies to solve unmet healthcare needs. His investments include companies using generative AI, semiconductors and deep learning to improve gene therapies, cancer detection, and antibody discovery. Before developing a career in venture capital investing, Vishal trained as a medical doctor and clinical scientist at the University of Oxford and at Imperial College, London as a UNESCO Fellow and a Rhodes Scholar. He then worked at the Wellcome Trust on strategy and policy around the Human Genome Project.In addition to his venture capital investing, Vishal also serves on the boards and investment committees of several funds, foundations, research bodies and academic institutions.

Biography
Swamy is a serial entrepreneur in interdisciplinary technologies. Having worked on novel sequencing methodologies and small molecule drug discovery platforms previously, he currently guides the integration of genomics tools in drug discovery at Zafrens. Swamy's interests are in decentralized and simplified access to high-resolution, high-throughput insights into biology.

Biography
David W. Craig, Ph.D., is an internationally recognized leader in developing and applying novel bioinformatics and genomics tools, as well as translating genomic discoveries from bench to bedside.Dr. Craig leads the Department of Integrative Translational Sciences, which focuses on precision measurement, data science and diversity. It will seek to further improve both translational outcomes, as well as the science underpinning the use of precision medicine.Dr. Craig leads the establishment of a transdisciplinary team of biologists and data scientists who will work with engineers, chemists and clinicians across the system to enhance City of Hopes patient-centered mission. He also will collaborate with regulatory agencies, industry partners, researchers and health care professionals to integrate scientific findings and translate potentially practice-changing discoveries into improved patient care and human health.He has spearheaded collaborative computational and data science efforts within large and small research consortiums, including the 1000 Genomes Project and the Bipolar Genome Study. His exceptional expertise has resulted in more than 200 publications, four patents and two founded companies. Dr. Craig earned his Ph.D. from the University of Washington, focusing on bioengineering. Dr. Craig joins City of Hope from the University of Southern California, where he was co-director of the Institute of Translational Genomics and vice chair of the Department of Translational Genomics at Keck School of Medicine of USC. He served as the director of the USC Norris Comprehensive Cancer Center Molecular Genomics Core and created their Translational Biomedical Informatics masters degree program. Before USC, Dr. Craig served as the deputy director of Bioinformatics at Translational Genomics Research Institute and as director of the Neurogenomics division.