Session Abstract – PMWC 2022 Silicon Valley


The PMWC 2021 Clinical & Research Tools Showcase will provide a 15-minute time slot for selected companies in this space. The Clinical & Research Tools is a showcase for innovative technologies that are used for the analysis of genetic variation and function, helping to advance breakthroughs in genetic health, rare disease conditions on individuals of all ages, complex diseases and cancer care. Next-generation sequencing (NGS) and microarray technologies empower rapidly evolving genomic revolution.


Confirmed Presenting Companies:

 Session Chair Profile

M.D., Research Physician, National Human Genome Research Institute, NIH

Biography
Alexander Katz is the principal investigator of the Genomic Ascertainment Cohort (TGAC) a large-scale resource enabling predictive genomic research. Dr. Katz leads a team of clinicians and bioinformaticians in implementing clinical research at the NIH clinical center that aims to predict phenotype from genotype. TGAC’s approach includes aggregating genomic data from a phenotypically unselected population and formulating hypotheses based on genomic variants of interest rather than phenotypic traits of interest. Dr. Katz is board certified in clinical genetics, molecular genetics, and internal medicine, having completed a clinical fellowship at the National Human Genome Research Institute and residency at the University of Michigan. He also holds a bachelor’s degree from the University of Virginia and a master’s degree in human genetics from the University of Michigan.


Clinical & Research Tools Showcase:
National Human Genome Research Institute, NIH

National Human Genome Research Institute aims to advance genomic research at the National Institutes of Health.

Piloting Predictive Medicine with TGAC
The Genomic Ascertainment Cohort (TGAC) represents a paradigm-shifting approach to clinical genomics research. By starting with a genomic variant of interest in an individual and performing deep targeted phenotyping, we predict phenotype from genotype - which ultimately can transform genomic medicine.

 Speaker Profile

Vice President of Bio-Pharmaceutical Solutions, Deep Lens

Biography
Kyle leads the strategy for Bio Pharmaceutical solutions with a laser-focused mission to identify and collaborate with game changers who want to speed precision diagnosis, treatment options, and hope. He is an industry innovator focused on developing solutions and businesses at the intersection of healthcare delivery & research, to drive better outcomes for patients. For over 20 years, Kyle has brought a passion and belief that meaningful change is possible across a diverse set of health system stakeholders by humbly challenging the status quo.


Clinical & Research Tools Showcase:
Deep Lens

Deep Lens is an innovative software company focused on a groundbreaking approach to faster recruitment of the best-suited cancer patients for clinical trials. By identifying patients at the time of diagnosis and combining lab, EMR and genomic data, VIPER, Deep Lens’ free integrated cloud platform for healthcare providers, provides care teams with visibility and workflows to accelerate recruitment and compress study timelines to bring game-changing therapies to market sooner.

 Speaker Profile

MA, International Economics; CEO, Deep 6 AI

Biography
Wout started his career as a diplomat in the Middle East before joining global management consulting firm, McKinsey & Company, serving a wide variety of industries across Asia. Next, Wout founded an extreme sports adventure company in Singapore and then spent five years in the high-stakes world of international security, growing and leading a 22,000-headcount organization across four continents into a $500M global player. Wout is a frequent speaker on artificial intelligence in healthcare and works closely with hospitals, pharma companies and research institutes on patient recruitment programs.


Clinical & Research Tools Showcase:
Deep 6 AI

Deep 6 AI finds more, better-matching patients for clinical trials in minutes rather than months. Using natural language processing to search unstructured data in medical records, our tool helps healthcare organizations and life sciences companies get life-saving cures to people more quickly.

Precision-matching: The Driver to High-performance Clinical Trials
Learn how a precision matching engine can drive performance throughout the entire clinical trial process. Wout will share the latest metrics & data, real world examples and a couple of surprising insights.

 Speaker Profile

Ph.D., CSO, Truckee Applied Genomics, LLC

Biography
Dr. Tian Yu is a Molecular Biologist experienced with life science/healthcare startups, currently focusing on leading products development in Truckee Applied Genomics and developing tools to improve the current covid testing by making it more affordable, more reliable, and keeping health care professionals safe from accidental viral exposures. Dr. Yu received her Ph.D. in biochemistry, molecular biology & cell biology in 2018. She has been published on topics such as epigenetic research for the interplay of RNA modifications and circular RNAs in the journal Cell Research. Before joining TAG, Dr. Yu has previously worked as an Assistant Core Director at the Single-Cell Sequencing Core, University of Nevada school of medicine, and then Bioelectronica as the lead biochemist where her research focused on developing life science tools for improving the antibody discovery workflow. The platform which she helped develop is now being placed in research labs across the globe.


Clinical & Research Tools Showcase:
Truckee Applied Genomics, LLC

Truckee Applied Genomics, LLC (TAG) is based in Reno Nevada and develops and manufactures patented reagents to improve molecular tests of tissues and pathogens.

New COVID-19 Surveillance Workflow With TAG-NGPM+
TAG-NGPM+ is the first specimen collection and transport media designed to improve safety for patients and lab staff by quickly inactivating virus while maintaining the sensitivity of molecular and rapid protein-based antigen assays. We propose a COVID-19 testing workflow that is designed to provide timely and accurate test results to patients and help with variant monitoring for effective transmission prevention and control.