Speaker Profile

Ph.D., Chief Scientific Officer, Complete Genomics, Inc. (a BGI company)
Biography

Dr. Radoje (Rade) Drmanac is one of the founders of the field of Genomics. He invented and led development of massively parallel DNA sequencing using DNA nanoarrays (Genomics 1989; Sci. Yugoslavica 1990, Science 1993), ligation-based DNA sequencing, and haplotyping by co-barcoded sequence reads. Currently he is Senior VP of BGI (Shenzhen, China) and CSO at Complete Genomics, Inc. (Mt. View, CA), which he co-founded in 2005 to develop efficient whole genome sequencing Science 2010, Nature 2012, Science 2012, Genome Research 2015). CGI was acquired by BGI in 2013. In 1994, he co-founded Hyseqand led discovery of thousands of novel genes. Earlier, he was at Argonne National Labs (1991-1994) as part of DOE Human Genome Project. He completed postdoctoral studies at ICRF in London. He started his career at the Center for Genetic Engineering, later IMGGI, in Belgrade, Serbia.He received his Ph.D. in Molecular Biology in 1988 at Belgrade University.

Talk

Efficient WGS as Foundation for Precision Medicine
A complete, accurate and phased WGS is critical to precision medicine. We describe an efficient massively parallel sequencing method using PCR-free process on patterned DNA-nanoball arrays, generating >1Tb (10 genomes) per microscope slide. When combined with co-barcoded reads, this platform generates the phased $100-WGS with quality needed for precision medicine.

Session Abstract – PMWC 2017 Silicon Valley

Session Synopsis: We explore the healthcare impact of a $100 genome. Whole Genome Sequencing at consumer pricing will give healthcare providers a wealth of information on genetic links, risk factors of diseases, drug targets and drug reactions. The availability of precision medicine will benefit patients and society while lowering cost.

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