M.D., Ph.D., Professor of Radiology and Bioengineering, UCSF
Dr. Mukherjee’s research has encompassed technical development and neuroscience applications of mapping microstructure, function and connectivity in the human brain, with the goal of developing novel imaging biomarkers for neurological and psychiatric diseases that can be used in a Precision Medicine framework for diagnosis, prognosis and treatment selection and monitoring. Recent work includes advanced diffusion MRI, fMRI and MEG to investigate cerebral connectivity in human brain development, neurodevelopmental disorders and traumatic brain injury (TBI). He serves as a PI and the Imaging Core leader for the US nationwide NIH Transforming Research and Clinical Knowledge in TBI (TRACK-TBI) study. He is also a PI of two NIH BRAIN Initiative projects to produce transformational advances in MRI technology for human brain imaging. Pratik Mukherjee MD PhD is Professor of Radiology and Bioengineering at the University of California, San Francisco (UCSF). He is a clinical neuroradiologist and also serves as the Director of the Center for Imaging of Neurodegenerative Disease at the San Francisco VA Medical Center. Dr. Mukherjee received his undergraduate degree in Computer Science and Psychology from Yale University, his PhD in Computational Neuroscience from Rockefeller University, and his MD from Cornell University.
Precision Imaging of the Human Brain Connectome
I review progress in mapping the human “connectome” (whole-brain large-scale connectivity network) using diffusion MRI and functional MRI, and its implications for the clinical neurosciences. The essential roles of Big Data and high-performance computing will be emphasized, with examples provided from recent international traumatic brain injury (TBI) research initiatives.