AI/Machine Learning in Healthcare – Hype or Reality?

Artificial Intelligence and machine learning are on everyones’ minds these days, and they are poised to become game changers in many areas, including the healthcare sector. There’s a rise in potential applications and companies developing new approaches and innovative tools and the industry is responding to this exciting development. Pharma is using AI to incorporate analytical solutions to accelerate drug development, the tech industry embracing the healthcare market to build winning solutions, and the clinical sector is utilizing AI for diagnostic and treatment decision making. While use in the clinic still remains on the horizon, huge strides are being made with its utility for drug design, discovery, and development including patient selection algorithms for clinical trials. All this comes as no surprise given the importance of the healthcare analytics market with an estimated size of $43B by 2024.

The benefits of a data-driven healthcare are manifold and undeniable. Yet, for AI and machine learning to create the value needed, significant hurdles must be overcome.  Traditional silos must be broken down and data must become accessible, managed and understood. Growth is largely driven by the providers’ ability to identify clinically meaningful outcomes in relation to costs, through the mining of EMR data, accelerated adoption of big data that enables informed patient decision-making, and the development of decision support tools for telehealth and remote patient monitoring. Standards of data collection and analytical methods are yet to be established. And   clinicians must be convinced and comfortable with placing their trust in “self-thinking” machines – no small task.

The debate is ongoing: Will AI replace human oncologists, as Vinod Khosla predicts?  It is only once we overcome these hurdles and have access to the data and the tools, that we can benefit from the advances of AI and machine learning, which should then become the key enablers of healthcare value?

Come and see for yourself – at PMWC 2018 Silicon Valley!
– Learn more about the speakers and topics here.

PMWC 2018 Silicon Valley has dedicated six sessions to AI and machine learning as well as a Company Showcase. This is a great opportunity for everybody in the field to learn, contribute, and help make AI a reality in healthcare. We have invited (and continue to invite) a number of leading scientists and critical thought leaders in AI and machine learning. Sessions include topics in the critical areas of data-driven patient care, population health, healthcare process automation, AI-enabled drug discovery and development, and the need to scale the infrastructure to meet the computationally intense demands of AI and machine learning.

Here is a list of thought leaders that are among the confirmed presenters:

With that we have some key players in the market presenting at the AI/machine learning track, including:

With that we have some key players in the market presenting at the AI/machine learning track, including:

I hope to see many of you join us for the approaching PMWC 2018 Silicon Valley, January 22-24, in Mountain View, CA for the AI Track that I am leading.

Best regards,


Dr. Eric Schadt
PMWC AI Track Chair
Founder and CEO
Sema4

Interview with Honoree Mary Relling, PMWC Duke 2018 Luminary Honoree

Q: Why is preemptive pharmacogenetics testing important in the context of personalized medicine?

A: We estimated that pharmacogenetic test results can impact the use of nearly 100 drugs, accounting for up to 18% of current prescriptions. Therefore, having pharmacogenetic test results already “in hand” at the time of prescribing will be more convenient for patients and physicians compared to performing as needed, one gene-at-a-time testing, which will be slower and more expensive.

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Interview with Eric Perakslis from Datavant

Q: What need is Datavant addressing?

A: While the volume of health data grows precipitously year over year, our ability to make use of that data is not keeping pace. There are many aspects to the inherent challenges and opportunities of this data explosion but of particular concern is the increased fragmentation.

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All of Us Research Program Aims to Create Diverse Research Data Resource

In the age of big DNA data, it is important to remember that accumulating large amounts of data is not enough. Equally important is keeping the DNA data that participants provide as diverse as possible to allow us to generate answers to questions about how different variables impact people differently.

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Interview with Philip Parks from Exact Sciences Corporation

Q: What need is Exact Sciences Corporation addressing?

A: Exact Sciences’ mission is to improve patient outcomes through the early detection of cancer. We are especially focused on developing highly accurate, minimally invasive screening tests and technologies.

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Interview with Mike Nall from Biocept, Inc.

Q: What need is Biocept, Inc addressing?

A: Physicians are not receiving all the genomic information needed for precision medicine therapeutic decision making so some patients potentially miss out on targeted therapies that could save or extend their lives.

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Interview with Michael Pellini from Section 32

Q: How do you select startup companies you invest in? What are values you are looking for both in the companies and the leadership teams?

A: This answer is more of a philosophical one rather than a simple listing of ingredients, even though the latter might be easier or more reassuring for an entrepreneur to digest.

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Jeff Gordon, The “Father of the Microbiome” On The Promises and Challenges of the Microbiome in Precision Medicine

The microbiome significantly impacts human health, playing a crucial role in maintaining health and preventing disease. It influences endocrinology, physiology, and even neurology, altering the outcome of many different disease states, and it has been shown to augment drug responses and tolerance. In parallel to your normal microbiota, headlining pathogens are grabbing our attention, as we seem to face a major epidemic or viral outbreak of some sort each year, whether it is Zika, Ebola, or the Coronavirus MERS-CoV.

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Q&A with Jeff Balser, Dean of Vanderbilt University School of Medicine, President & CEO VUMC

Q: What is your vision for personalized care?

A: While the term “personalized care” has become popular contemporary with the maturation of genomic medicine, it is clear that the entire context of care – including social, behavioral, and environmental factors – drives the outcomes we are hoping to achieve.

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Q&A with All of Us Research Program Deputy Director Stephanie Devaney, Ph.D.

Q1a: You are the Deputy Director of the All of Us Research Program. What is your role as the deputy director and why is this initiative so important?

A: As deputy director, my primary role is to work closely with the All of Us Director Eric Dishman in guiding the program from concept to reality. Our vision is to enable a healthier future for all of us by building a data resource that scientists can use to speed up research and the development of individualized approaches to prevention and treatment.

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Interview with Honoree Jeffrey Gordon, PMWC 2018 Duke Luminary Honoree

Q: Why is the microbiome so important in the context of precision medicine?

A: We can’t ignore a part of our body that is composed of tens and tens of trillions cells, albeit microbial – a population that collectively contains at least two orders of magnitude more genes than in our Homo sapiens genome, endows us with attributes and capabilities that we have not had to evolve on our own, and contributes to our intra- and interpersonal biological variations as well as health status.

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Call to the Health Care Community to Execute on Next Steps for a Wider Adoption and Implementation of Precision Medicine

The recent Facebook data breach, genetic data sleuthing by the FBI that led to the Golden State Killer, and the soon-to-be-implemented European General Data Protection Regulation (GDPR), has put data privacy and security front and center.

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Data Privacy, the Security, And Ownership

The recent Facebook data breach, genetic data sleuthing by the FBI that led to the Golden State Killer, and the soon-to-be-implemented European General Data Protection Regulation (GDPR), has put data privacy and security front and center.

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Q&A with Jason Crites from IBM & Piers Nash from Health2047 Speaking at PMWC 2018 Michigan in June

Q: What need is IBM and Health2047 addressing in the healthcare/life sciences sector?

Jason (IBM): The industry is undergoing a significant transformation as reimbursement shifts from fee-for-service to value-based outcomes in the face of regulatory uncertainty.

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Dr. Francis Collins of NIH at June PMWC Michigan- Launch of Nationwide Participation Enrollment!

This past Sunday—May 6, 2018—the program reached a major milestone with the start of the nationwide participation enrollment! The All of Us Research Program, part of the Precision Medicine Initiative that was famously announced by President Barack Obama at the 2015 State of the Union address, aims to enroll a total of 1 million Americans.

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Meet Dr. Gil Omenn, Director of the University of Michigan Center for Computational Medicine & Bioinformatics on June 6th at PMWC 2018 Michigan

Q: What are the objectives of the Human Proteome Project and what are some of the recent breakthrough discoveries?

The HUPO Human Proteome Project has two overarching goals: (1) to complete the protein parts list, with at least one protein product from each of the ~20,000 protein-coding genes along with sequence variants, splice variants, and post-translational modifications, with characterization of their functions;…

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University of Michigan

The Precision Medicine World Conference (PMWC), held annually in Silicon Valley, is coming back to North Carolina for its 2nd Conference back at Duke University on September 24-25, 2018.

PMWC 2018 Duke, the 15th installment of the conference, will spotlight the explosion of biomedical technologies, driving initiatives that enable the translation of precision medicine into direct improvements in health care.

 

  • Track 1 will showcase sessions on the latest advancements in precision medicine which include, but are not limited to:
    • Digital Phenotyping
    • Precision Public Health
    • Pharmacogenomics
    • The Microbiome
    • Rare Disease Diagnosis
    • Digital Health/Health and Wellness
    • Early Days of Life Sequencing
    • Diversity in Precision Medicine
    • Resilience
    • AI and Machine Learning
    • Gene Editing
    • Large Scale Bio-data Resources to Support Drug Development (PPPs)
    • Point-of Care Dx Platform
    • FDA Efforts to Accelerate PM
    • Implementation into Health Care Delivery
    • Next Gen. Workforce of PM
    • Immunotherapy
    • Robust Clinical Decision Support Tools
    • Creating Clinical Value with Liquid Biopsy ctDNA, etc.
    • Neoantigens
    • Emerging Technologies In PM

The Precision Medicine World Conference (PMWC), held annually in Silicon Valley, is coming back to North Carolina for its 2nd Conference back at Duke University on September 24-25, 2018.

PMWC 2018 Duke, the 15th installment of the conference, will spotlight the explosion of biomedical technologies, driving initiatives that enable the translation of precision medicine into direct improvements in health care.

 

    • Track 1 will showcase sessions on the latest advancements in precision medicine which include, but are not limited to:
      • Digital Phenotyping
      • Precision Public Health
      • Pharmacogenomics
      • The Microbiome
      • Rare Disease Diagnosis
      • Digital Health/Health and Wellness
      • Early Days of Life Sequencing
      • Diversity in Precision Medicine
      • Resilience
      • AI and Machine Learning
      • Gene Editing
      • Large Scale Bio-data Resources
        to Support Drug Development (PPPs)
      • Point-of Care Dx Platform
      • FDA Efforts to Accelerate PM
      • Implementation into Health Care Delivery
      • Next Gen. Workforce of PM
      • Immunotherapy
      • Robust Clinical Decision Support Tools
      • Creating Clinical Value with Liquid Biopsy
        ctDNA, etc.
      • Neoantigens
      • Emerging Technologies In PM
  • Track 2- PMWC 2018 Duke Showcase, will enable 15-minute company presentations on latest novel technologies. Apply to present here.
big data diagnostics session

Clinical Dx Showcase

crispr showcase

Emerging Therapeutics Showcase

NGS Showcase

Genomic Profiling Showcase

AI Showcase Session Image

AI and Data Sciences Showcase

  • Luminary and Pioneer Awards, honoring individuals who contributed, and continue to contribute, to the field of Precision Medicine
  • 500+ multidisciplinary attendees, from across the entire spectrum of healthcare, representing different types of companies, technologies, and medical centers with leadership roles in precision medicine

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