Q: What are some of the large programs currently under way at the University of Oxford to help develop the space of precision medicine? What are some specifics and how will they help overcome precision medicine challenges?

A: The University of Oxford houses one of the largest (and internationally most highly rated) biomedical research campuses in Europe. Many of the research programmes, from basic science to clinical translation, offer potential for improvements in precision medicine. Some specific examples include large programmes in human genetics, cardiovascular medicine, cancer, medical imaging, tropical medicine and infectious disease, biomedical big data, and neurodegenerative disease.

Q: Oxford just opened the largest big data institute, the BDI. What are some of the institute’s goals and how will they be tackled? What can we expect to learn over the next 1-5 years?

A: The potential for insights from big data in biomedical research is huge, and the challenges are substantial. Oxford University’s new Big Data Institute is an interdisciplinary research centre which focuses on the analysis of large, complex, heterogeneous data sets for research into the causes and consequences, prevention, and treatment of disease. BDI researchers develop, evaluate, and deploy efficient methods for acquiring and analysing information for large clinical research studies. These approaches are invaluable in identifying the associations between lifestyle exposures, genetic variants, infections and health outcomes around the globe.

Q: Large-scale programs, like the 100,000 Genomes Projects, have been put in place to further advance precision medicine. With these programs, what are some of the key components that will change and drive the success of precision medicine? What are some challenges we still need to overcome?

A: The 100,000 Genomes Project in the UK is a forerunner for more extensive collection and use of genomic information in clinical medicine. It has been a pioneer in addressing some of the logistical, ethical, and bioinformatics challenges in undertaking genome sequencing at scale in clinical medicine.

Q: Volumes of data is getting generated with the Human Genome Project. What kind of challenges is human genetic data giving to science and how can we overcome these challenges?

A: The cost of sequencing human genomes has dropped dramatically, to the extent that whole genome and whole exome sequencing is increasingly undertaken in research studies and some areas within clinical medicine. A major challenge, and a focus of the Global Alliance for Genomics and Health (GA4GH) is to facilitate responsible sharing of as much of this data as is possible.

Q: How will genomics transform healthcare and how will it impact medicine? Beyond genetics and genomics what other data is relevant and why?

A: There will be an explosion in the extent of genomic data, with as many as 1 billion people sequenced within 10-15 years. In many cases the genetic data will be linked to information about the individuals, through electronic medical records, or data from wearables, or both. This presents an enormous opportunity to better understand fundamental human biology, in health and in disease. We will learn the typical response of an individual to a therapeutic or a treatment, and also better understand the variability in this response between individuals. Both will have a huge role to play in informing drug development, from target identification, through understanding mechanism and choosing biomarkers, to the design of clinical trials. It will also inform clinical choices of treatment for the individual.

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Q: As a pioneer in high performance architectures for genomic research what are the biggest challenges that you see clients dealing with as they invest in precision medicine initiatives?

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Q: Immunotherapy is considered a huge game-changer and holds a lot of promises. Is the hype around immunotherapy justified? What are some of the exciting developments in the recent years?

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Q: CellMax has developed non-invasive blood tests based on Circulating tumor cells CTC. How do you see these tests being adopted clinically?

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Q: What are the benefits of the Precision BioSciences’ ARCUS genome editing platform and what makes it unique?

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Q: Olink has been rapidly growing its’ library of human protein biomarker assays. What are the popular clinical applications for your biomarker panels?

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University of Michigan

About us:
The Precision Medicine World Conference (PMWC), in its 13th installment, will take place in Silicon Valley on January 22-24, 2018. The program will traverse innovative technologies, thriving initiatives, and clinical case studies that enable the translation of precision medicine into direct improvements in health care. Conference attendees will have an opportunity to learn first-hand about the latest developments and advancements in precision medicine and cutting-edge new strategies and solutions that are changing how patients are treated.

Agenda highlights:

    • More than 70 sessions with 350+ thought-provoking, insightful talks that cover all facets of precision medicine
    • Four tracks will showcase sessions on the latest advancements in precision medicine which include, but are not limited to:
    • Immuno-oncology
    • Cancer and rare disease diagnostics
    • Biomarker and companion diagnostics
    • Big data approaches
    • NGS applications
    • AI and machine learning applications
    • Advancements in liquid biopsy applications
    • Wellness & Aging
    • CRISPR
    • The human microbiome
    • Infectious disease ID and monitoring
    • The importance of patient engagement
    • 3-D technologies
    • Updates on data and regulatory policies
    • Metabolomics in precision medicine
    • mHealth and Telehealth

About us:
The Precision Medicine World Conference (PMWC), in its 13th installment, will take place in Silicon Valley on January 22-24, 2018. The program will traverse innovative technologies, thriving initiatives, and clinical case studies that enable the translation of precision medicine into direct improvements in health care. Conference attendees will have an opportunity to learn first-hand about the latest developments and advancements in precision medicine and cutting-edge new strategies and solutions that are changing how patients are treated.

Agenda highlights:

    • More than 70 sessions with 350+ thought-provoking, insightful talks that cover all facets of precision medicine
    • Four tracks will showcase sessions on the latest advancements in precision medicine which include, but are not limited to:
        • Immuno-oncology
        • Cancer and rare disease diagnostics
        • Biomarker and companion diagnostics
        • Big data approaches
        • NGS applications
        • AI and machine learning applications
        • Advancements in liquid biopsy applications
        • Wellness & Aging
        • CRISPR
        • The human microbiome
        • Infectious disease identification and monitoring
        • The importance of patient engagement
        • 3-D technologies
        • Updates on data and regulatory policies
        • Metabolomics in precision medicine
        • mHealth and Telehealth

One track will be dedicated to the various aspects of the All of Us Research Program, while another session will focus on educating California’s legislators.

 

Confirmed thought leaders include:

Sir John Bell

Sir John Bell

Regius Professor of Medicine, Oxford University

sally-davies

Dame Sally Davies

Chief Medical Officer, Department of Health, UK Government

BLA00002-Elizabeth-Blackburn

Elizabeth Blackburn

Nobel Laureate, President, Salk Institute for Biological Studies

George-Sledge

George Sledge

Professor, Division Chief, Stanford University Medical Center

Jeffrey Bluestone

Jeffrey Bluestone

CEO and President, Parker Institute for Cancer Immunotherapy

Christopher Ianelli

Christopher Ianelli

Founder and Chief Executive Officer,  iSpecimen

Kenneth J. Pienta

Kenneth J. Pienta

Director, Brady Urological Institute, Johns Hopkins Medicine

Roy Beveridge

Roy Beveridge

Senior Vice President & Chief Medical Officer, Humana

Kimberly Blackwell

Kimberly Blackwell

Professor of Medicine, Assistant Prof. of Radiation Oncology, Duke Cancer Institute

Joshua Denny

Joshua Denny

Professor of Biomedical Informatics & Medicine, Vanderbilt University Medical Center

Edward S. Kim

Edward S. Kim

Chair, Solid Tumor and Investigational Therapeutics, Levine Cancer Institute

Howard L. McLeod

Howard L. McLeod

Medical Director, Personalized Medicine Institute, Moffitt Cancer Center

Lee Newcomer

Lee Newcomer

SVP, UnitedHealthcare Oncology and Genetics

Vinod Khosla

Vinod Khosla

Partner and Founder of Khosla Ventures

Troy Brennan

Troy Brennan

Executive VP & CMO, CVS Health

Ira Mellman

Ira Mellman

VP, Cancer Immunology, Genentech

Event Highlights

When
January 22, 2018 8:00am to January 24, 2018 5:00pm
Where
Computer History Museum
1401 N Shoreline Blvd
Mountain View, CA 94043
Cost
$1850 by January 19th, 2018
Registration
3-Day Access to Talks, Exhibition & Reception:
See Registration Details

Registration: PMWC Conferences

Silicon Valley Jan 22-24, 2018

65+ Sessions 4 Tracks
350+ Speaker lineup
Access to the exhibition
Breakfast & lunch refreshments
Networking App
Award Reception

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